Leibold, Josef

Senolytic CAR T cells reverse senescence-associated pathologies

Amor, C., Feucht, J., Leibold, J., Ho, Y.-J., Zhu, C., Alonso-Curbelo, D., Mansilla-Soto, J., Boyer, J. A., Li, X., Giavridis, T., et al. (2020) · Nature

Telomeres, Telomerase, and SenescenceCAR-T cell therapy research

Cited by 1,098

Calibration of CAR activation potential directs alternative T cell fates and therapeutic potency

Feucht, J., Sun, J., Eyquem, J., Ho, Y.-J., Zhao, Z., Leibold, J., Dobrin, A., Cabriolu, A., Hamieh, M., & Sadelain, M. (2019) · Nature Medicine

CAR-T cell therapy researchT-cell and B-cell Immunology

Cited by 547

Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer

Ruscetti, M., Morris, J. P., Mezzadra, R., Russell, J., Leibold, J., Romesser, P. B., Simon, J., Kulick, A., Ho, Y.-J., Fennell, M., et al. (2020) · Cell

Pancreatic and Hepatic Oncology ResearchTelomeres, Telomerase, and Senescence

Cited by 424

NK cell–mediated cytotoxicity contributes to tumor control by a cytostatic drug combination

Ruscetti, M., Leibold, J., Bott, M. J., Fennell, M., Kulick, A., Salgado, N. R., Chen, C.-C., Ho, Y.-J., Sanchez-Rivera, F. J., Feucht, J., et al. (2018) · Science

Immune Cell Function and InteractionTelomeres, Telomerase, and Senescence

Cited by 415

In vivo RNAi screening identifies a mechanism of sorafenib resistance in liver cancer

Rudalska, R., Dauch, D., Longerich, T., McJunkin, K., Wuestefeld, T., Kang, T.-W., Hohmeyer, A., Pesic, M., Leibold, J., von Thun, A., et al. (2014) · Nature Medicine

Hepatocellular Carcinoma Treatment and PrognosisColorectal Cancer Treatments and Studies

Cited by 282

The Oncogenic Action of NRF2 Depends on De-glycation by Fructosamine-3-Kinase

Sanghvi, V. R., Leibold, J., Mina, M., Mohan, P., Berishaj, M., Li, Z., Miele, M. M., Lailler, N., Zhao, C., de Stanchina, E., et al. (2019) · Cell

Genomics, phytochemicals, and oxidative stressRedox biology and oxidative stress

Cited by 155

Senescence-induced vascular remodeling creates therapeutic vulnerabilities in pancreas cancer

Ruscetti, M., Morris, J. P., Mezzadra, R., Russell, J., Leibold, J., Romesser, P. B., Simon, J., Kulick, A., Ho, Y.-J., Fennell, M., et al. (2021) · Cell

Pancreatic and Hepatic Oncology ResearchTelomeres, Telomerase, and Senescence

Cited by 46