Lazo, John S.

microRNA-21 negatively regulates Cdc25A and cell cycle progression in colon cancer cells

Wang, P., Zou, F., Zhang, X., Li, H., Dulak, A., Tomko, R. J., Lazo, J. S., Wang, Z., Zhang, L., & Yu, J. (2009) · Cancer Research

MicroRNA in disease regulationCancer-related Molecular Pathways

Cited by 308

The Liver X Receptor Ligand T0901317 Decreases Amyloid β Production in Vitro and in a Mouse Model of Alzheimer's Disease

Koldamova, R. P., Lefterov, I. M., Staufenbiel, M., Wolfe, D., Huang, S., Glorioso, J. C., Walter, M., Roth, M. G., & Lazo, J. S. (2005) · Journal of Biological Chemistry

Alzheimer's disease research and treatmentsCholesterol and Lipid Metabolism

Cited by 279

22R-Hydroxycholesterol and 9-cis-Retinoic Acid Induce ATP-binding Cassette Transporter A1 Expression and Cholesterol Efflux in Brain Cells and Decrease Amyloid β Secretion

Koldamova, R. P., Lefterov, I. M., Ikonomovic, M. D., Skoko, J., Lefterov, P. I., Isanski, B. A., DeKosky, S. T., & Lazo, J. S. (2003) · Journal of Biological Chemistry

Cholesterol and Lipid MetabolismAlzheimer's disease research and treatments

Cited by 237

The Substrate Recognition Domains of the N-end Rule Pathway

Tasaki, T., Zakrzewska, A., Dudgeon, D. D., Jiang, Y., Lazo, J. S., & Kwon, Y. T. (2009) · Journal of Biological Chemistry

Ubiquitin and proteasome pathwaysProtein Degradation and Inhibitors

Cited by 149

Apolipoprotein A-I Directly Interacts with Amyloid Precursor Protein and Inhibits Aβ Aggregation and Toxicity

Koldamova, R. P., Lefterov, I. M., Lefterova, M. I., & Lazo, J. S. (2001) · Biochemistry

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 131

Direct inhibition of c-Myc-Max heterodimers by celastrol and celastrol-inspired triterpenoids

Wang, H., Teriete, P., Hu, A., Raveendra-Panickar, D., Pendelton, K., Lazo, J. S., Eiseman, J., Holien, T., Misund, K., Oliynyk, G., et al. (2015) · Oncotarget

Natural Compounds in Disease TreatmentNatural product bioactivities and synthesis

Cited by 53

Reduced brain insulin signaling: A seminal process in Alzheimer's disease pathogenesis

Bloom, G. S., Lazo, J. S., & Norambuena, A. (2018) · Neuropharmacology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 44