Kishimoto, Takashi Kei

Polymeric synthetic nanoparticles for the induction of antigen-specific immunological tolerance

Maldonado, R. A., LaMothe, R. A., Ferrari, J. D., Zhang, A.-H., Rossi, R. J., Kolte, P. N., Griset, A. P., O’Neil, C., Altreuter, D. H., Browning, E., et al. (2015) · Proceedings of the National Academy of Sciences

Immunotherapy and Immune ResponsesT-cell and B-cell Immunology

Cited by 441

Antigen-selective modulation of AAV immunogenicity with tolerogenic rapamycin nanoparticles enables successful vector re-administration

Meliani, A., Boisgerault, F., Hardet, R., Marmier, S., Collaud, F., Ronzitti, G., Leborgne, C., Costa Verdera, H., Simon Sola, M., Charles, S., et al. (2018) · Nature Communications

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 265

Improving the efficacy and safety of biologic drugs with tolerogenic nanoparticles

Kishimoto, T. K., Ferrari, J. D., LaMothe, R. A., Kolte, P. N., Griset, A. P., O'Neil, C., Chan, V., Browning, E., Chalishazar, A., Kuhlman, W., et al. (2016) · Nature Nanotechnology

Immunotherapy and Immune ResponsesNanoparticle-Based Drug Delivery

Cited by 201

Addressing high dose AAV toxicity – ‘one and done’ or ‘slower and lower’

Kishimoto, T. K., & Samulski, R. J. (2022) · Expert Opinion on Biological Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 152

Tolerogenic nanoparticles mitigate the formation of anti-drug antibodies against pegylated uricase in patients with hyperuricemia

Sands, E., Kivitz, A., DeHaan, W., Leung, S. S., Johnston, L., & Kishimoto, T. K. (2022) · Nature Communications

Gout, Hyperuricemia, Uric AcidDrug-Induced Adverse Reactions

Cited by 61

Enhancement of liver-directed transgene expression at initial and repeat doses of AAV vectors admixed with ImmTOR nanoparticles

Ilyinskii, P. O., Michaud, A. M., Roy, C. J., Rizzo, G. L., Elkins, S. L., Capela, T., Chowdhury, A. C., Leung, S. S., & Kishimoto, T. K. (2021) · Science Advances

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 56

ImmTOR nanoparticles enhance AAV transgene expression after initial and repeat dosing in a mouse model of methylmalonic acidemia

Ilyinskii, P. O., Michaud, A. M., Rizzo, G. L., Roy, C. J., Leung, S. S., Elkins, S. L., Capela, T., Chowdhury, A., Li, L., Chandler, R. J., et al. (2021) · Molecular Therapy - Methods & Clinical Development

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 39