Molday, Robert S.

Transgenic mice with a rhodopsin mutation (Pro23His): A mouse model of autosomal dominant retinitis pigmentosa

Olsson, J. E., Gordon, J. W., Pawlyk, B. S., Roof, D., Hayes, A., Molday, R. S., Mukai, S., Cowley, G. S., Berson, E. L., & Dryja, T. P. (1992) · Neuron

Retinal Development and DisordersPhotoreceptor and optogenetics research

Cited by 455

Retinal Stimulates ATP Hydrolysis by Purified and Reconstituted ABCR, the Photoreceptor-specific ATP-binding Cassette Transporter Responsible for Stargardt Disease

Sun, H., Molday, R. S., & Nathans, J. (1999) · Journal of Biological Chemistry

Drug Transport and Resistance MechanismsRetinal Development and Disorders

Cited by 353

ABCA4 is an N-retinylidene-phosphatidylethanolamine and phosphatidylethanolamine importer

Quazi, F., Lenevich, S., & Molday, R. S. (2012) · Nature Communications

Retinal Development and DisordersDrug Transport and Resistance Mechanisms

Cited by 276

ABCR expression in foveal cone photoreceptors and its role in Stargardt macular dystrophy

Molday, L. L., Rabin, A. R., & Molday, R. S. (2000) · Nature Genetics

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 269

Photoreceptors at a glance

Molday, R. S., & Moritz, O. L. (2015) · Journal of Cell Science

Retinal Development and DisordersPhotoreceptor and optogenetics research

Cited by 235

The ATP-Binding Cassette Transporter ABCA4: Structural and Functional Properties and Role in Retinal Disease

Tsybovsky, Y., Molday, R. S., & Palczewski, K. (2010) · Advances in Experimental Medicine and Biology

Retinal Development and DisordersDrug Transport and Resistance Mechanisms

Cited by 200

The role of the photoreceptor ABC transporter ABCA4 in lipid transport and Stargardt macular degeneration

Molday, R. S., Zhong, M., & Quazi, F. (2009) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 182

Localization, purification, and functional reconstitution of the P4-ATPase Atp8a2, a phosphatidylserine flippase in photoreceptor disc membranes

Coleman, J. A., Kwok, M. C. M., & Molday, R. S. (2009) · Journal of Biological Chemistry

Lipid Membrane Structure and BehaviorATP Synthase and ATPases Research

Cited by 181

N-Retinylidene-phosphatidylethanolamine Is the Preferred Retinoid Substrate for the Photoreceptor-specific ABC Transporter ABCA4 (ABCR)

Beharry, S., Zhong, M., & Molday, R. S. (2004) · Journal of Biological Chemistry

Retinal Development and DisordersDrug Transport and Resistance Mechanisms

Cited by 174

Membrane Topology of the ATP Binding Cassette Transporter ABCR and Its Relationship to ABC1 and Related ABCA Transporters

Bungert, S., Molday, L. L., & Molday, R. S. (2001) · Journal of Biological Chemistry

Drug Transport and Resistance MechanismsRetinal Development and Disorders

Cited by 173

ATP-binding cassette transporter ABCA4 and chemical isomerization protect photoreceptor cells from the toxic accumulation of excess 11- cis -retinal

Quazi, F., & Molday, R. S. (2014) · Proceedings of the National Academy of Sciences

Retinal Development and DisordersRetinoids in leukemia and cellular processes

Cited by 129

Structure and function of ABCA4 and its role in the visual cycle and Stargardt macular degeneration

Molday, R. S., Garces, F. A., Scortecci, J. F., & Molday, L. L. (2022) · Progress in Retinal and Eye Research

Retinal Development and DisordersDrug Transport and Resistance Mechanisms

Cited by 107

Defective lipid transport and biosynthesis in recessive and dominant Stargardt macular degeneration

Molday, R. S., & Zhang, K. (2010) · Progress in Lipid Research

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 82

Insights into the Molecular Properties of ABCA4 and Its Role in the Visual Cycle and Stargardt Disease

Molday, R. S. (2015) · Progress in Molecular Biology and Translational Science

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 70

Dual ABCA4 -AAV Vector Treatment Reduces Pathogenic Retinal A2E Accumulation in a Mouse Model of Autosomal Recessive Stargardt Disease

Dyka, F. M., Molday, L. L., Chiodo, V. A., Molday, R. S., & Hauswirth, W. W. (2019) · Human Gene Therapy

Retinal Development and DisordersVirus-based gene therapy research

Cited by 56

Molecular Organization and ATP-Induced Conformational Changes of ABCA4, the Photoreceptor-Specific ABC Transporter

Tsybovsky, Y., Orban, T., Molday, R. S., Taylor, D., & Palczewski, K. (2013) · Structure

Drug Transport and Resistance MechanismsATP Synthase and ATPases Research

Cited by 53

Posttranslational Modifications of the Photoreceptor-Specific ABC Transporter ABCA4

Tsybovsky, Y., Wang, B., Quazi, F., Molday, R. S., & Palczewski, K. (2011) · Biochemistry

Retinal Development and DisordersDrug Transport and Resistance Mechanisms

Cited by 39

Binding of N-Retinylidene-Pe to BACA4 and a Model for its Transport Across Membranes

Molday, R. S., Beharry, S., Ahn, J., & Zhong, M. (2007) · Advances in Experimental Medicine and Biology

Retinal Development and DisordersDrug Transport and Resistance Mechanisms

Cited by 27

Retinal gene therapy for Stargardt disease with dual AAV intein vectors is both safe and effective in large animal models

Ferla, R., Pugni, E., Lupo, M., Tiberi, P., Fioretto, F., Perota, A., Duchi, R., Lagutina, I., Gesualdo, C., Rossi, S., et al. (2025) · Science Advances

Retinal Development and DisordersVirus-based gene therapy research

Cited by 19

Subretinal Gene Delivery Using Helper-Dependent Adenoviral Vectors

Wu, L., Lam, S., Cao, H., Guan, R., Duan, R., van der Kooy, D., Bremner, R., Molday, R. S., & Hu, J. (2011) · Cell & Bioscience

Virus-based gene therapy researchRetinal Development and Disorders

Cited by 13