Howell, Jessica J.

Stimulation of de novo pyrimidine synthesis by growth signaling through mTOR and S6K1

Ben-Sahra, I., Howell, J. J., Asara, J. M., & Manning, B. D. (2013) · Science

Biochemical and Molecular ResearchPI3K/AKT/mTOR signaling in cancer

Cited by 739

A Novel Hypoxia-inducible Factor-independent Hypoxic Response Regulating Mammalian Target of Rapamycin and Its Targets

Arsham, A. M., Howell, J. J., & Simon, M. C. (2003) · Journal of Biological Chemistry

PI3K/AKT/mTOR signaling in cancerCancer, Hypoxia, and Metabolism

Cited by 463

Metformin Inhibits Hepatic Mtorc1 Signaling via Dose-Dependent Mechanisms Involving AMPK and the TSC Complex

Howell, J. J., Hellberg, K., Turner, M., Talbott, G., Kolar, M. J., Ross, D. S., Hoxhaj, G., Saghatelian, A., Shaw, R. J., & Manning, B. D. (2017) · Cell Metabolism

Metabolism, Diabetes, and CancerPI3K/AKT/mTOR signaling in cancer

Cited by 408

Discovery of NV-5138, the first selective Brain mTORC1 activator

Sengupta, S., Giaime, E., Narayan, S., Hahm, S., Howell, J., O’Neill, D., Vlasuk, G. P., & Saiah, E. (2019) · Scientific Reports

PI3K/AKT/mTOR signaling in cancerAutophagy in Disease and Therapy

Cited by 72