Sime, Patricia J.

Lactic Acid Is Elevated in Idiopathic Pulmonary Fibrosis and Induces Myofibroblast Differentiation via pH-Dependent Activation of Transforming Growth Factor-β

Kottmann, R. M., Kulkarni, A. A., Smolnycki, K. A., Lyda, E., Dahanayake, T., Salibi, R., Honnons, S., Jones, C., Isern, N. G., Hu, J. Z., et al. (2012) · American Journal of Respiratory and Critical Care Medicine

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisPulmonary Hypertension Research and Treatments

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PPAR-γ Ligands Repress TGFβ-Induced Myofibroblast Differentiation by Targeting the PI3K/Akt Pathway: Implications for Therapy of Fibrosis

Kulkarni, A. A., Thatcher, T. H., Olsen, K. C., Maggirwar, S. B., Phipps, R. P., & Sime, P. J. (2011) · PLoS ONE

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisTGF-β signaling in diseases

Cited by 189

Differences in the Fibrogenic Response after Transfer of Active Transforming Growth Factor- β 1 Gene to Lungs of “Fibrosis-prone” and “Fibrosis-resistant” Mouse Strains

Kolb, M., Bonniaud, P., Galt, T., Sime, P. J., Kelly, M. M., Margetts, P. J., & Gauldie, J. (2002) · American Journal of Respiratory Cell and Molecular Biology

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisTGF-β signaling in diseases

Cited by 168

Asbestos-Derived Reactive Oxygen Species Activate TGF-Β1

Pociask, D. A., Sime, P. J., & Brody, A. R. (2004) · Laboratory Investigation

TGF-β signaling in diseasesOccupational and environmental lung diseases

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Inflammasome formation in the lungs of patients with fatal COVID-19

Toldo, S., Bussani, R., Nuzzi, V., Bonaventura, A., Mauro, A. G., Cannatà, A., Pillappa, R., Sinagra, G., Nana-Sinkam, P., Sime, P., et al. (2021) · Inflammation Research

Inflammasome and immune disordersCOVID-19 Clinical Research Studies

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SIRT1 protects against cigarette smoke-induced lung oxidative stress via a FOXO3-dependent mechanism

Yao, H., Sundar, I. K., Ahmad, T., Lerner, C., Gerloff, J., Friedman, A. E., Phipps, R. P., Sime, P. J., McBurney, M. W., Guarente, L., et al. (2014) · American Journal of Physiology-Lung Cellular and Molecular Physiology

Sirtuins and Resveratrol in MedicineChronic Obstructive Pulmonary Disease (COPD) Research

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