Franzese, Ornella

p38 signaling inhibits mTORC1-independent autophagy in senescent human CD8+ T cells

Henson, S. M., Lanna, A., Riddell, N. E., Franzese, O., Macaulay, R., Griffiths, S. J., Puleston, D. J., Watson, A. S., Simon, A. K., Tooze, S. A., et al. (2014) · Journal of Clinical Investigation

Telomeres, Telomerase, and SenescenceAutophagy in Disease and Therapy

Cited by 389

KLRG1 signaling induces defective Akt (ser473) phosphorylation and proliferative dysfunction of highly differentiated CD8+ T cells

Henson, S. M., Franzese, O., Macaulay, R., Libri, V., Azevedo, R. I., Kiani-Alikhan, S., Plunkett, F. J., Masters, J. E., Jackson, S., Griffiths, S. J., et al. (2009) · Blood

T-cell and B-cell ImmunologyTelomeres, Telomerase, and Senescence

Cited by 262

The loss of telomerase activity in highly differentiated CD8+CD28−CD27− T cells is associated with decreased Akt (Ser473) phosphorylation

Plunkett, F. J., Franzese, O., Finney, H. M., Fletcher, J. M., Belaramani, L. L., Salmon, M., Dokal, I., Webster, D., Lawson, A. D. G., & Akbar, A. N. (2007) · The Journal of Immunology

Telomeres, Telomerase, and SenescenceT-cell and B-cell Immunology

Cited by 222

The impact of telomere erosion on memory CD8+ T cells in patients with X-linked lymphoproliferative syndrome

Plunkett, F. J., Franzese, O., Belaramani, L. L., Fletcher, J. M., Gilmour, K. C., Sharifi, R., Khan, N., Hislop, A. D., Cara, A., Salmon, M., et al. (2005) · Mechanisms of Ageing and Development

Telomeres, Telomerase, and SenescenceT-cell and B-cell Immunology

Cited by 74

IFN-α Inhibits Telomerase in Human CD8+ T Cells by Both hTERT Downregulation and Induction of p38 MAPK Signaling

Lanna, A., Coutavas, E., Levati, L., Seidel, J., Rustin, M. H. A., Henson, S. M., Akbar, A. N., & Franzese, O. (2013) · The Journal of Immunology

Telomeres, Telomerase, and SenescenceT-cell and B-cell Immunology

Cited by 62

Reversal of functional defects in highly differentiated young and old CD8 T cells by PDL blockade

Henson, S. M., Macaulay, R., Franzese, O., & Akbar, A. N. (2012) · Immunology

T-cell and B-cell ImmunologyCancer Immunotherapy and Biomarkers

Cited by 42

Defect in HSP90 expression in highly differentiated human CD8+ T lymphocytes

Franzese, O., Henson, S. M., Naro, C., & Bonmassar, E. (2014) · Cell Death & Disease

T-cell and B-cell ImmunologyHeat shock proteins research

Cited by 8