Osborne, Cameron S

LMO2 -Associated Clonal T Cell Proliferation in Two Patients after Gene Therapy for SCID-X1

Hacein-Bey-Abina, S., Von Kalle, C., Schmidt, M., McCormack, M. P., Wulffraat, N., Leboulch, P., Lim, A., Osborne, C. S., Pawliuk, R., Morillon, E., et al. (2003) · Science

Virus-based gene therapy researchCAR-T cell therapy research

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Mapping long-range promoter contacts in human cells with high-resolution capture Hi-C

Mifsud, B., Tavares-Cadete, F., Young, A. N., Sugar, R., Schoenfelder, S., Ferreira, L., Wingett, S. W., Andrews, S., Grey, W., Ewels, P. A., et al. (2015) · Nature Genetics

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

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Long-range chromatin regulatory interactions in vivo

Carter, D., Chakalova, L., Osborne, C. S., Dai, Y.-F., & Fraser, P. (2002) · Nature Genetics

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

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The pluripotent regulatory circuitry connecting promoters to their long-range interacting elements

Schoenfelder, S., Furlan-Magaril, M., Mifsud, B., Tavares-Cadete, F., Sugar, R., Javierre, B.-M., Nagano, T., Katsman, Y., Sakthidevi, M., Wingett, S. W., et al. (2015) · Genome Research

Genomics and Chromatin DynamicsChromosomal and Genetic Variations

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CHiCAGO: robust detection of DNA looping interactions in Capture Hi-C data

Cairns, J., Freire-Pritchett, P., Wingett, S. W., Várnai, C., Dimond, A., Plagnol, V., Zerbino, D., Schoenfelder, S., Javierre, B.-M., Osborne, C., et al. (2016) · Genome Biology

Genomics and Chromatin DynamicsBioinformatics and Genomic Networks

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Polycomb repressive complex PRC1 spatially constrains the mouse embryonic stem cell genome

Schoenfelder, S., Sugar, R., Dimond, A., Javierre, B.-M., Armstrong, H., Mifsud, B., Dimitrova, E., Matheson, L., Tavares-Cadete, F., Furlan-Magaril, M., et al. (2015) · Nature Genetics

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

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Global reorganisation of cis-regulatory units upon lineage commitment of human embryonic stem cells

Freire-Pritchett, P., Schoenfelder, S., Várnai, C., Wingett, S. W., Cairns, J., Collier, A. J., García-Vílchez, R., Furlan-Magaril, M., Osborne, C. S., Fraser, P., et al. (2017) · eLife

Genomics and Chromatin DynamicsPluripotent Stem Cells Research

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Large scale loss of data in low-diversity Illumina sequencing libraries can be recovered by deferred cluster calling

Krueger, F., Andrews, S. R., & Osborne, C. S. (2011) · PLoS ONE

Genomics and Phylogenetic StudiesSingle-cell and spatial transcriptomics

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