Jaeschke, Hartmut

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1

Klionsky, D. J., Abdel-Aziz, A. K., Abdelfatah, S., Abdellatif, M., Abdoli, A., Abel, S., Abeliovich, H., Abildgaard, M. H., Abudu, Y. P., Acevedo-Arozena, A., et al. (2021) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

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Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME

Godoy, P., Hewitt, N. J., Albrecht, U., Andersen, M. E., Ansari, N., Bhattacharya, S., Bode, J. G., Bolleyn, J., Borner, C., Böttger, J., et al. (2013) · Archives of Toxicology

Drug-Induced Hepatotoxicity and ProtectionLiver physiology and pathology

Cited by 1,280

Bile Acids Induce Inflammatory Genes in Hepatocytes

Allen, K., Jaeschke, H., & Copple, B. L. (2011) · The American Journal of Pathology

Liver physiology and pathologyImmune Response and Inflammation

Cited by 501

Novel Mechanisms of Protection Against Acetaminophen Hepatotoxicity in Mice by Glutathione and N-Acetylcysteine

Saito, C., Zwingmann, C., & Jaeschke, H. (2010) · Hepatology

Drug-Induced Hepatotoxicity and ProtectionSulfur Compounds in Biology

Cited by 430

Peroxynitrite-induced mitochondrial and endonuclease-mediated nuclear DNA damage in acetaminophen hepatotoxicity

Cover, C., Mansouri, A., Knight, T. R., Bajt, M. L., Lemasters, J. J., Pessayre, D., & Jaeschke, H. (2005) · The Journal of Pharmacology and Experimental Therapeutics

Drug-Induced Hepatotoxicity and ProtectionMitochondrial Function and Pathology

Cited by 373

Nrf2 promotes the development of fibrosis and tumorigenesis in mice with defective hepatic autophagy

Ni, H.-M., Woolbright, B. L., Williams, J., Copple, B., Cui, W., Luyendyk, J. P., Jaeschke, H., & Ding, W.-X. (2014) · Journal of Hepatology

Autophagy in Disease and TherapyLiver physiology and pathology

Cited by 270

Farnesoid X receptor critically determines the fibrotic response in mice but is expressed to a low extent in human hepatic stellate cells and periductal myofibroblasts

Fickert, P., Fuchsbichler, A., Moustafa, T., Wagner, M., Zollner, G., Halilbasic, E., Stöger, U., Arrese, M., Pizarro, M., Solís, N., et al. (2009) · The American Journal of Pathology

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 169

Translocation of iron from lysosomes into mitochondria is a key event during oxidative stress-induced hepatocellular injury

Uchiyama, A., Kim, J.-S., Kon, K., Jaeschke, H., Ikejima, K., Watanabe, S., & Lemasters, J. J. (2008) · Hepatology

Iron Metabolism and DisordersMitochondrial Function and Pathology

Cited by 154

Neutrophil-mediated tissue injury in alcoholic hepatitis

Jaeschke, H. (2002) · Alcohol

Alcohol Consumption and Health EffectsLiver physiology and pathology

Cited by 150

Delayed Treatment With 4-Methylpyrazole Protects Against Acetaminophen Hepatotoxicity in Mice by Inhibition of c-Jun n-Terminal Kinase

Akakpo, J. Y., Ramachandran, A., Duan, L., Schaich, M. A., Jaeschke, M. W., Freudenthal, B. D., Ding, W.-X., Rumack, B. H., & Jaeschke, H. (2019) · Toxicological Sciences

Drug-Induced Hepatotoxicity and ProtectionPoisoning and overdose treatments

Cited by 105

Recovered hepatocytes promote macrophage apoptosis through CXCR4 after acetaminophen-induced liver injury in mice

Nguyen, N. T., Umbaugh, D. S., Huang, E. L., Adelusi, O. B., Sanchez Guerrero, G., Ramachandran, A., & Jaeschke, H. (2022) · Toxicological Sciences

Drug-Induced Hepatotoxicity and ProtectionLiver physiology and pathology

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