Frost, Georgia R.

The innate immunity protein IFITM3 modulates γ-secretase in Alzheimer’s disease

Hur, J.-Y., Frost, G. R., Wu, X., Crump, C., Pan, S. J., Wong, E., Barros, M., Li, T., Nie, P., Zhai, Y., et al. (2020) · Nature

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 382

AD-linked R47H- TREM2 mutation induces disease-enhancing microglial states via AKT hyperactivation

Sayed, F. A., Kodama, L., Fan, L., Carling, G. K., Udeochu, J. C., Le, D., Li, Q., Zhou, L., Wong, M. Y., Horowitz, R., et al. (2021) · Science Translational Medicine

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 155

Hypoxia Inducible Factor-1α binds and activates γ-secretase for Aβ production under hypoxia and cerebral hypoperfusion

Alexander, C., Li, T., Hattori, Y., Chiu, D., Frost, G. R., Jonas, L., Liu, C., Anderson, C. J., Wong, E., Park, L., et al. (2022) · Molecular Psychiatry

Alzheimer's disease research and treatmentsNeurological Disease Mechanisms and Treatments

Cited by 64

AD-linked R47H- TREM2 mutation induces disease-enhancing proinflammatory microglial states in mice and humans

Sayed, F. A., Kodama, L., Udeochu, J. C., Fan, L., Carling, G. K., Le, D., Li, Q., Zhou, L., Mathys, H., Wang, M., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory)

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 3