Leone, Paola

Differential involvement of ventral tegmental mu, delta and kappa opioid receptors in modulation of basal mesolimbic dopamine release: in vivo microdialysis studies.

Devine, D. P., Leone, P., Pocock, D., & Wise, R. A. (1993) · The Journal of Pharmacology and Experimental Therapeutics

Neuropeptides and Animal PhysiologyNeurotransmitter Receptor Influence on Behavior

Cited by 382

Long-term follow-up after gene therapy for canavan disease

Leone, P., Shera, D., McPhee, S. W. J., Francis, J. S., Kolodny, E. H., Bilaniuk, L. T., Wang, D.-J., Assadi, M., Goldfarb, O., Goldman, H. W., et al. (2012) · Science Translational Medicine

Virus-based gene therapy researchLysosomal Storage Disorders Research

Cited by 307

Gene Therapy of Canavan Disease: AAV-2 Vector for Neurosurgical Delivery of Aspartoacylase Gene ( ASPA ) to the Human Brain

Janson, C., McPhee, S., Bilaniuk, L., Haselgrove, J., Testaiuti, M., Freese, A., Wang, D.-J., Shera, D., Hurh, P., Rupin, J., et al. (2002) · Human Gene Therapy

Virus-based gene therapy researchLysosomal Storage Disorders Research

Cited by 255

Immune responses to AAV in a phase I study for Canavan disease

McPhee, S. W. J., Janson, C. G., Li, C., Samulski, R. J., Camp, A. S., Francis, J., Shera, D., Lioutermann, L., Feely, M., Freese, A., et al. (2006) · The Journal of Gene Medicine

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 241

SCH 23390 blocks drug-conditioned place-preference and place-aversion: anhedonia (lack of reward) or apathy (lack of motivation) after dopamine-receptor blockade

Acquas, E., Carboni, E., Leone, P., & Di Chiara, G. (1989) · Psychopharmacology

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 207

Quantitative comparison of expression with adeno-associated virus (AAV-2) brain-specific gene cassettes

Xu, R., Janson, C., Mastakov, M., Lawlor, P., Young, D., Mouravlev, A., Fitzsimons, H., Choi, K.-L., Ma, H., Dragunow, M., et al. (2001) · Gene Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 174

Natural History of Canavan Disease Revealed by Proton Magnetic Resonance Spectroscopy (1H‐MRS) and Diffusion-weighted MRI

Janson, C., McPhee, S., Francis, J., Shera, D., Assadi, M., Freese, A., Hurh, P., Haselgrove, J., Wang, D., Bilaniuk, L., et al. (2006) · Neuropediatrics

Metabolism and Genetic DisordersAdvanced MRI Techniques and Applications

Cited by 82

Clinical Applications Involving CNS Gene Transfer

Kantor, B., McCown, T., Leone, P., & Gray, S. J. (2014) · Advances in Genetics

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 74

N-acetylaspartate supports the energetic demands of developmental myelination via oligodendroglial aspartoacylase

Francis, J. S., Wojtas, I., Markov, V., Gray, S. J., McCown, T. J., Samulski, R. J., Bilaniuk, L. T., Wang, D.-J., De Vivo, D. C., Janson, C. G., et al. (2016) · Neurobiology of Disease

Metabolism and Genetic DisordersVirus-based gene therapy research

Cited by 49

Aspartoacylase supports oxidative energy metabolism during myelination

Francis, J. S., Strande, L., Markov, V., & Leone, P. (2012) · Journal of Cerebral Blood Flow & Metabolism

Metabolism and Genetic DisordersAmino Acid Enzymes and Metabolism

Cited by 41

Preclinical biodistribution, tropism, and efficacy of oligotropic AAV/Olig001 in a mouse model of congenital white matter disease

Francis, J. S., Markov, V., Wojtas, I. D., Gray, S., McCown, T., Samulski, R. J., Figueroa, M., & Leone, P. (2021) · Molecular Therapy - Methods & Clinical Development

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 41

Oncology and Pharmacogenomics Insights in Polycystic Ovary Syndrome: An Integrative Analysis

Yumiceba, V., López-Cortés, A., Pérez-Villa, A., Yumiseba, I., Guerrero, S., García-Cárdenas, J. M., Armendáriz-Castillo, I., Guevara-Ramírez, P., Leone, P. E., Zambrano, A. K., et al. (2020) · Frontiers in Endocrinology

Ovarian function and disordersOvarian cancer diagnosis and treatment

Cited by 40

Endogenous aspartoacylase expression is responsive to glutamatergic activity in vitro and in vivo

Francis, J. S., Strande, L., Pu, A., & Leone, P. (2011) · Glia

Neurogenesis and neuroplasticity mechanismsAmino Acid Enzymes and Metabolism

Cited by 12