Déglon, Nicole

The JAK/STAT3 pathway is a common inducer of astrocyte reactivity in Alzheimer’s and Huntington’s diseases

Ben Haim, L., Ceyzériat, K., Carrillo-de Sauvage, M. A., Aubry, F., Auregan, G., Guillermier, M., Ruiz, M., Petit, F., Houitte, D., Faivre, E., et al. (2015) · The Journal of Neuroscience

Neuroinflammation and Neurodegeneration MechanismsCytokine Signaling Pathways and Interactions

Cited by 335

BDNF overexpression in mouse hippocampal astrocytes promotes local neurogenesis and elicits anxiolytic-like activities

Quesseveur, G., David, D. J., Gaillard, M. C., Pla, P., Wu, M. V., Nguyen, H. T., Nicolas, V, Auregan, G., David, I., Dranovsky, A., et al. (2013) · Translational Psychiatry

Neurogenesis and neuroplasticity mechanismsTreatment of Major Depression

Cited by 235

Human Induced Pluripotent Stem Cell-Derived Astrocytes Are Differentially Activated by Multiple Sclerosis-Associated Cytokines

Perriot, S., Mathias, A., Perriard, G., Canales, M., Jonkmans, N., Merienne, N., Meunier, C., El Kassar, L., Perrier, A. L., Laplaud, D.-A., et al. (2018) · Stem Cell Reports

Neuroinflammation and Neurodegeneration MechanismsPluripotent Stem Cells Research

Cited by 171

Engineered lentiviral vector targeting astrocytes In vivo

Colin, A., Faideau, M., Dufour, N., Auregan, G., Hassig, R., Andrieu, T., Brouillet, E., Hantraye, P., Bonvento, G., & Déglon, N. (2009) · Glia

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 158

Different tau species lead to heterogeneous tau pathology propagation and misfolding

Dujardin, S., Bégard, S., Caillierez, R., Lachaud, C., Carrier, S., Lieger, S., Gonzalez, J. A., Deramecourt, V., Déglon, N., Maurage, C.-A., et al. (2018) · Acta Neuropathologica Communications

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 109

Beclin 1 mitigates motor and neuropathological deficits in genetic mouse models of Machado–Joseph disease

Nascimento-Ferreira, I., Nóbrega, C., Vasconcelos-Ferreira, A., Onofre, I., Albuquerque, D., Aveleira, C., Hirai, H., Déglon, N., & Pereira de Almeida, L. (2013) · Brain

Genetic Neurodegenerative DiseasesAmyotrophic Lateral Sclerosis Research

Cited by 96

Efficient gene delivery and selective transduction of astrocytes in the mammalian brain using viral vectors

Merienne, N., Douce, J. L., Faivre, E., Déglon, N., & Bonvento, G. (2013) · Frontiers in Cellular Neuroscience

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 58

The striatal kinase DCLK3 produces neuroprotection against mutant huntingtin

Galvan, L., Francelle, L., Gaillard, M.-C., de Longprez, L., Carrillo-de Sauvage, M.-A., Liot, G., Cambon, K., Stimmer, L., Luccantoni, S., Flament, J., et al. (2018) · Brain

Genetic Neurodegenerative DiseasesGenetics and Neurodevelopmental Disorders

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A neuronal MCT2 knockdown in the rat somatosensory cortex reduces both the NMR lactate signal and the BOLD response during whisker stimulation

Mazuel, L., Blanc, J., Repond, C., Bouchaud, V., Raffard, G., Déglon, N., Bonvento, G., Pellerin, L., & Bouzier-Sore, A.-K. (2017) · PLoS ONE

Advanced MRI Techniques and ApplicationsNeuroscience and Neuropharmacology Research

Cited by 44

Coupling of D2R Short but not D2R Long receptor isoform to the Rho/ROCK signaling pathway renders striatal neurons vulnerable to mutant huntingtin

Galan‐Rodriguez, B., Martin, E., Brouillet, E., Déglon, N., Betuing, S., & Caboche, J. (2017) · European Journal of Neuroscience

Genetic Neurodegenerative DiseasesReceptor Mechanisms and Signaling

Cited by 5