Wakita, Masahiro

Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells

Takahashi, A., Loo, T. M., Okada, R., Kamachi, F., Watanabe, Y., Wakita, M., Watanabe, S., Kawamoto, S., Miyata, K., Barber, G. N., et al. (2018) · Nature Communications

Telomeres, Telomerase, and Senescenceinterferon and immune responses

Cited by 350

A BET family protein degrader provokes senolysis by targeting NHEJ and autophagy in senescent cells

Wakita, M., Takahashi, A., Sano, O., Loo, T. M., Imai, Y., Narukawa, M., Iwata, H., Matsudaira, T., Kawamoto, S., Ohtani, N., et al. (2020) · Nature Communications

Telomeres, Telomerase, and SenescenceProtein Degradation and Inhibitors

Cited by 206

SARS-CoV-2 infection triggers paracrine senescence and leads to a sustained senescence-associated inflammatory response

Tsuji, S., Minami, S., Hashimoto, R., Konishi, Y., Suzuki, T., Kondo, T., Sasai, M., Torii, S., Ono, C., Shichinohe, S., et al. (2022) · Nature Aging

Telomeres, Telomerase, and SenescenceCOVID-19 Clinical Research Studies

Cited by 84

Comparative analysis of senolytic drugs reveals mitochondrial determinants of efficacy and resistance

Wakita, M., Ito, K., Fujii, K., Sakamoto, D., Mikawa, T., Sugawara, S., Zhou, X., Park, J. H., Miyagawa, H., Motooka, D., et al. (2026) · Nature Aging

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 9