Irvine, Darrell J.
Howard Hughes Medical Institute · Ragon Institute of MGH, MIT and Harvard · Koch Institute for Integrative Cancer Research At MIT · Massachusetts Institute of Technology
9 papers on CoChatORCID 0000-0002-8637-1405
Most cited papers
- Verified
Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia
Metallo, C. M., Gameiro, P. A., Bell, E. L., Mattaini, K. R., Yang, J., Hiller, K., Jewell, C. M., Johnson, Z. R., Irvine, D. J., Guarente, L., et al. (2012) · Nature
Cancer, Hypoxia, and MetabolismCancer, Lipids, and Metabolism
Cited by 1,791
- Verified
T cell‐targeting nanoparticles focus delivery of immunotherapy to improve antitumor immunity
Schmid, D., Park, C. G., Hartl, C. A., Subedi, N., Cartwright, A. N., Puerto, R. B., Zheng, Y., Maiarana, J., Freeman, G. J., Wucherpfennig, K. W., et al. (2017) · Nature Communications
Nanoparticle-Based Drug DeliveryCancer Immunotherapy and Biomarkers
Cited by 449
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Slow Delivery Immunization Enhances HIV Neutralizing Antibody and Germinal Center Responses via Modulation of Immunodominance
Cirelli, K. M., Carnathan, D. G., Nogal, B., Martin, J. T., Rodriguez, O. L., Upadhyay, A. A., Enemuo, C. A., Gebru, E. H., Choe, Y., Viviano, F., et al. (2019) · Cell
HIV Research and TreatmentSARS-CoV-2 and COVID-19 Research
Cited by 433
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Sustained antigen availability during germinal center initiation enhances antibody responses to vaccination
Tam, H. H., Melo, M. B., Kang, M., Pelet, J. M., Ruda, V. M., Foley, M. H., Hu, J. K., Kumari, S., Crampton, J., Baldeon, A. D., et al. (2016) · Proceedings of the National Academy of Sciences
HIV Research and TreatmentImmunotherapy and Immune Responses
Cited by 425
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In Vitro and in Vivo mRNA Delivery Using Lipid-Enveloped pH-Responsive Polymer Nanoparticles
Su, X., Fricke, J., Kavanagh, D. G., & Irvine, D. J. (2011) · Molecular Pharmaceutics
RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery
Cited by 287
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Multifunctional oncolytic nanoparticles deliver self-replicating IL-12 RNA to eliminate established tumors and prime systemic immunity
Li, Y., Su, Z., Zhao, W., Zhang, X., Momin, N., Zhang, C., Wittrup, K. D., Dong, Y., Irvine, D. J., & Weiss, R. (2020) · Nature Cancer
Immunotherapy and Immune ResponsesRNA Interference and Gene Delivery
Cited by 233
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Immunogenicity of RNA Replicons Encoding HIV Env Immunogens Designed for Self-Assembly into Nanoparticles
Melo, M., Porter, E., Zhang, Y., Silva, M., Li, N., Dobosh, B., Liguori, A., Skog, P., Landais, E., Menis, S., et al. (2019) · Molecular Therapy
RNA Interference and Gene DeliveryHIV Research and Treatment
Cited by 88
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In vitro evolution of enhanced RNA replicons for immunotherapy
Li, Y., Teague, B., Zhang, Y., Su, Z., Porter, E., Dobosh, B., Wagner, T., Irvine, D. J., & Weiss, R. (2019) · Scientific Reports
RNA Interference and Gene DeliveryVirus-based gene therapy research
Cited by 71
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Rapid Germinal Center and Antibody Responses in Non-human Primates after a Single Nanoparticle Vaccine Immunization
Havenar-Daughton, C., Carnathan, D. G., Boopathy, A. V., Upadhyay, A. A., Murrell, B., Reiss, S. M., Enemuo, C. A., Gebru, E. H., Choe, Y., Dhadvai, P., et al. (2019) · Cell Reports
Immunotherapy and Immune ResponsesT-cell and B-cell Immunology
Cited by 58
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