Vollrath, Douglas

Mutations in MERTK, the human orthologue of the RCS rat retinal dystrophy gene, cause retinitis pigmentosa

Gal, A., Li, Y., Thompson, D. A., Weir, J., Orth, U., Jacobson, S. G., Apfelstedt-Sylla, E., & Vollrath, D. (2000) · Nature Genetics

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 679

mTOR-mediated dedifferentiation of the retinal pigment epithelium initiates photoreceptor degeneration in mice

Zhao, C., Yasumura, D., Li, X., Matthes, M., Lloyd, M., Nielsen, G., Ahern, K., Snyder, M., Bok, D., Dunaief, J. L., et al. (2011) · Journal of Clinical Investigation

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 303

Correction of the retinal dystrophy phenotype of the RCS rat by viral gene transfer of Mertk

Vollrath, D., Feng, W., Duncan, J. L., Yasumura, D., D'Cruz, P. M., Chappelow, A., Matthes, M. T., Kay, M. A., & LaVail, M. M. (2001) · Proceedings of the National Academy of Sciences

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 290

Mertk triggers uptake of photoreceptor outer segments during phagocytosis by cultured retinal pigment epithelial cells

Feng, W., Yasumura, D., Matthes, M. T., LaVail, M. M., & Vollrath, D. (2002) · Journal of Biological Chemistry

Retinal Development and DisordersPhagocytosis and Immune Regulation

Cited by 244

Treatment of retinitis pigmentosa due to MERTK mutations by ocular subretinal injection of adeno-associated virus gene vector: results of a phase I trial

Ghazi, N. G., Abboud, E. B., Nowilaty, S. R., Alkuraya, H., Alhommadi, A., Cai, H., Hou, R., Deng, W.-T., Boye, S. L., Almaghamsi, A., et al. (2016) · Human Genetics

Retinal Development and DisordersVirus-based gene therapy research

Cited by 243

Generation of Cre Transgenic Mice with Postnatal RPE-Specific Ocular Expression

Iacovelli, J., Zhao, C., Wolkow, N., Veldman, P., Gollomp, K., Ojha, P., Lukinova, N., King, A., Feiner, L., Esumi, N., et al. (2011) · Investigative Opthalmology & Visual Science

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 89

Mertk drives myosin II redistribution during retinal pigment epithelial phagocytosis

Strick, D. J., Feng, W., & Vollrath, D. (2009) · Investigative Opthalmology & Visual Science

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 81

Tyro3 modulates Mertk-associated retinal degeneration

Vollrath, D., Yasumura, D., Benchorin, G., Matthes, M. T., Feng, W., Nguyen, N. M., Sedano, C. D., Calton, M. A., & LaVail, M. M. (2015) · PLoS Genetics

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 66