Covey, Douglas F.
Washington University in St. Louis · Taylor Family Institute for Innovative Psychiatric Research
9 papers on CoChatORCID 0000-0002-9316-8683
Most cited papers
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Lysosomal cholesterol activates mTORC1 via an SLC38A9–Niemann-Pick C1 signaling complex
Castellano, B. M., Thelen, A. M., Moldavski, O., Feltes, M., van der Welle, R. E. N., Mydock-McGrane, L., Jiang, X., van Eijkeren, R. J., Davis, O. B., Louie, S. M., et al. (2017) · Science
PI3K/AKT/mTOR signaling in cancerAutophagy in Disease and Therapy
Cited by 562
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Neurosteroids as novel antidepressants and anxiolytics: GABA-A receptors and beyond
Zorumski, C. F., Paul, S. M., Covey, D. F., & Mennerick, S. (2019) · Neurobiology of Stress
Neuroscience and Neuropharmacology ResearchTreatment of Major Depression
Cited by 305
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Oxysterols are allosteric activators of the oncoprotein Smoothened
Nachtergaele, S., Mydock, L. K., Krishnan, K., Rammohan, J., Schlesinger, P. H., Covey, D. F., & Rohatgi, R. (2012) · Nature Chemical Biology
Hedgehog Signaling Pathway StudiesSphingolipid Metabolism and Signaling
Cited by 284
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Cholesterol Stabilizes TAZ in Hepatocytes to Promote Experimental Non-alcoholic Steatohepatitis
Wang, X., Cai, B., Yang, X., Sonubi, O. O., Zheng, Z., Ramakrishnan, R., Shi, H., Valenti, L., Pajvani, U. B., Sandhu, J., et al. (2020) · Cell Metabolism
Liver Disease Diagnosis and TreatmentLiver physiology and pathology
Cited by 204
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25-Hydroxycholesterol amplifies microglial IL-1β production in an apoE isoform-dependent manner
Wong, M. Y., Lewis, M., Doherty, J. J., Shi, Y., Cashikar, A. G., Amelianchik, A., Tymchuk, S., Sullivan, P. M., Qian, M., Covey, D. F., et al. (2020) · Journal of Neuroinflammation
Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments
Cited by 121
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Neurosteroid Analog Photolabeling of a Site in the Third Transmembrane Domain of the β3 Subunit of the GABAA Receptor
Chen, Z.-W., Manion, B., Townsend, R. R., Reichert, D. E., Covey, D. F., Steinbach, J. H., Sieghart, W., Fuchs, K., & Evers, A. S. (2012) · Molecular Pharmacology
Neuroscience and Neuropharmacology ResearchReceptor Mechanisms and Signaling
Cited by 72
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A Proinflammatory Stimulus Disrupts Hippocampal Plasticity and Learning via Microglial Activation and 25-Hydroxycholesterol
Izumi, Y., Cashikar, A. G., Krishnan, K., Paul, S. M., Covey, D. F., Mennerick, S. J., & Zorumski, C. F. (2021) · The Journal of Neuroscience
Neuroinflammation and Neurodegeneration MechanismsNeuroscience and Neuropharmacology Research
Cited by 53
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The enantiomer of progesterone (ent-progesterone) is a competitive inhibitor of human cytochromes P450c17 and P450c21
Auchus, R. J., Sampath Kumar, A., Andrew Boswell, C., Gupta, M. K., Bruce, K., Rath, N. P., & Covey, D. F. (2003) · Archives of Biochemistry and Biophysics
Steroid Chemistry and BiochemistryMetal-Catalyzed Oxygenation Mechanisms
Cited by 39
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Solid-state NMR observation of cysteine and lysine Michael adducts of inactivated estradiol dehydrogenase
Auchus, R. J., Covey, D. F., Bork, V, & Schaefer, J. (1988) · Journal of Biological Chemistry
Advanced NMR Techniques and ApplicationsSteroid Chemistry and Biochemistry
Cited by 18
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