Roche, Philippe

Chemical and structural lessons from recent successes in protein–protein interaction inhibition (2P2I)

Morelli, X., Bourgeas, R., & Roche, P. (2011) · Current Opinion in Chemical Biology

Computational Drug Discovery MethodsChemical Synthesis and Analysis

Cited by 223

2P2Idb: a structural database dedicated to orthosteric modulation of protein–protein interactions

Basse, M. J., Betzi, S., Bourgeas, R., Bouzidi, S., Chetrit, B., Hamon, V., Morelli, X., & Roche, P. (2012) · Nucleic Acids Research

Computational Drug Discovery MethodsProtein Structure and Dynamics

Cited by 148

Atomic Analysis of Protein-Protein Interfaces with Known Inhibitors: The 2P2I Database

Bourgeas, R., Basse, M.-J., Morelli, X., & Roche, P. (2010) · PLoS ONE

Computational Drug Discovery MethodsProtein Structure and Dynamics

Cited by 126

2P2Idb v2: update of a structural database dedicated to orthosteric modulation of protein–protein interactions

Basse, M.-J., Betzi, S., Morelli, X., & Roche, P. (2016) · Database

Computational Drug Discovery MethodsProtein Structure and Dynamics

Cited by 83

A gain-of-function RAC2 mutation is associated with bone-marrow hypoplasia and an autosomal dominant form of severe combined immunodeficiency

Lagresle-Peyrou, C., Olichon, A., Sadek, H., Roche, P., Tardy, C., Silva, C. D., Garrigue, A., Fischer, A., Moshous, D., Collette, Y., et al. (2020) · Haematologica

Immunodeficiency and Autoimmune DisordersBlood disorders and treatments

Cited by 35