Taylor, Justin

Somatic mutations and cell identity linked by Genotyping of Transcriptomes

Nam, A. S., Kim, K.-T., Chaligne, R., Izzo, F., Ang, C., Taylor, J., Myers, R. M., Abu-Zeinah, G., Brand, R., Omans, N. D., et al. (2019) · Nature

Single-cell and spatial transcriptomicsMyeloproliferative Neoplasms: Diagnosis and Treatment

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Acquired resistance to IDH inhibition through trans or cis dimer-interface mutations

Intlekofer, A. M., Shih, A. H., Wang, B., Nazir, A., Rustenburg, A. S., Albanese, S. K., Patel, M., Famulare, C., Correa, F. M., Takemoto, N., et al. (2018) · Nature

Acute Myeloid Leukemia ResearchGlioma Diagnosis and Treatment

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Synthetic Lethal and Convergent Biological Effects of Cancer-Associated Spliceosomal Gene Mutations

Lee, S. C.-W., North, K., Kim, E., Jang, E., Obeng, E., Lu, S. X., Liu, B., Inoue, D., Yoshimi, A., Ki, M., et al. (2018) · Cancer Cell

RNA Research and SplicingAcute Myeloid Leukemia Research

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Kinase-impaired BTK mutations are susceptible to clinical-stage BTK and IKZF1/3 degrader NX-2127

Montoya, S., Bourcier, J., Noviski, M., Lu, H., Thompson, M. C., Chirino, A., Jahn, J., Sondhi, A. K., Gajewski, S., Tan, Y. S. (., et al. (2024) · Science

Chronic Lymphocytic Leukemia ResearchProtein Degradation and Inhibitors

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BTK inhibitors: past, present, and future

Cool, A., Nong, T., Montoya, S., & Taylor, J. (2024) · Trends in Pharmacological Sciences

Chronic Lymphocytic Leukemia ResearchProtein Degradation and Inhibitors

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E7820, an anti-cancer sulfonamide, degrades RBM39 in patients with splicing factor mutant myeloid malignancies: a phase II clinical trial

Bewersdorf, J. P., Stahl, M., Taylor, J., Mi, X., Chandhok, N. S., Watts, J., Derkach, A., Wysocki, M., Lu, S. X., Bourcier, J., et al. (2023) · Leukemia

Acute Myeloid Leukemia ResearchRNA Research and Splicing

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XPO1 Overexpression Is a Mechanism of Resistance to Eprenetapopt and 5-Azacitidine Therapy That Can be Therapeutically Exploited for the Treatment of TP53 Mutated Myeloid Malignancies

Kruer, T. L., Quintana, A., Ferrall-Fairbanks, M., Zhang, L., Newman, H., McLemore, A. F., Yang, Q., Bencrentsil, N., Komrokji, R. S., Chaudhry, S., et al. (2022) · Blood

Acute Myeloid Leukemia ResearchCancer-related Molecular Pathways

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