Cowan, Angus D.

Trivalent PROTACs enhance protein degradation via combined avidity and cooperativity

Imaide, S., Riching, K. M., Makukhin, N., Vetma, V., Whitworth, C., Hughes, S. J., Trainor, N., Mahan, S. D., Murphy, N., Cowan, A. D., et al. (2021) · Nature Chemical Biology

Protein Degradation and InhibitorsChemical Synthesis and Analysis

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Targeted protein degradation via intramolecular bivalent glues

Hsia, O., Hinterndorfer, M., Cowan, A. D., Iso, K., Ishida, T., Sundaramoorthy, R., Nakasone, M. A., Imrichova, H., Schätz, C., Rukavina, A., et al. (2024) · Nature

Protein Degradation and InhibitorsUbiquitin and proteasome pathways

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Scalable insect cell expression and purification screening applied to CRL4-DCAF substrate receptors

Cowan, A. D., Jaekel, S., & Ciulli, A. (2025) · Protein Expression and Purification

Viral Infectious Diseases and Gene Expression in InsectsUbiquitin and proteasome pathways

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