Wierda, Keimpe

Tau association with synaptic vesicles causes presynaptic dysfunction

Zhou, L., McInnes, J., Wierda, K., Holt, M., Herrmann, A. G., Jackson, R. J., Wang, Y.-C., Swerts, J., Beyens, J., Miskiewicz, K., et al. (2017) · Nature Communications

Alzheimer's disease research and treatmentsNeuroscience and Neuropharmacology Research

Cited by 434

Mitochondria metabolism sets the species-specific tempo of neuronal development

Iwata, R., Casimir, P., Erkol, E., Boubakar, L., Planque, M., Gallego López, I. M., Ditkowska, M., Gaspariunaite, V., Beckers, S., Remans, D., et al. (2023) · Science

Neurogenesis and neuroplasticity mechanismsMitochondrial Function and Pathology

Cited by 312

Secreted amyloid-β precursor protein functions as a GABA B R1a ligand to modulate synaptic transmission

Rice, H. C., de Malmazet, D., Schreurs, A., Frere, S., Van Molle, I., Volkov, A. N., Creemers, E., Vertkin, I., Nys, J., Ranaivoson, F. M., et al. (2019) · Science

Neuroscience and Neuropharmacology ResearchAlzheimer's disease research and treatments

Cited by 281

Synaptogyrin-3 Mediates Presynaptic Dysfunction Induced by Tau

McInnes, J., Wierda, K., Snellinx, A., Bounti, L., Wang, Y.-C., Stancu, I.-C., Apóstolo, N., Gevaert, K., Dewachter, I., Spires-Jones, T. L., et al. (2018) · Neuron

Alzheimer's disease research and treatmentsNeuroscience and Neuropharmacology Research

Cited by 242

Synaptic neoteny of human cortical neurons requires species-specific balancing of SRGAP2-SYNGAP1 cross-inhibition

Libé-Philippot, B., Iwata, R., Recupero, A. J., Wierda, K., Bernal Garcia, S., Hammond, L., van Benthem, A., Limame, R., Ditkowska, M., Beckers, S., et al. (2024) · Neuron

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 38

SYNGAP1 deficiency disrupts synaptic neoteny in xenotransplanted human cortical neurons in vivo

Vermaercke, B., Iwata, R., Wierda, K., Boubakar, L., Rodriguez, P., Ditkowska, M., Bonin, V., & Vanderhaeghen, P. (2024) · Neuron

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 27