Lohoff, Falk W.

Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4

Psychiatric GWAS Consortium Bipolar Disorder Working Group, Sklar, P., Ripke, S., Scott, L. J., Andreassen, O. A., Cichon, S., Craddock, N., Edenberg, H. J., Nurnberger, J. I., Rietschel, M., et al. (2011) · Nature Genetics

Bipolar Disorder and TreatmentGenetic Associations and Epidemiology

Cited by 1,344

Overview of the Genetics of Major Depressive Disorder

Lohoff, F. W. (2010) · Current Psychiatry Reports

Genetic Associations and EpidemiologyTreatment of Major Depression

Cited by 498

Genome-wide association study of bipolar disorder in European American and African American individuals

Smith, E. N., Bloss, C. S., Badner, J. A., Barrett, T., Belmonte, P. L., Berrettini, W., Byerley, W., Coryell, W., Craig, D., Edenberg, H. J., et al. (2009) · Molecular Psychiatry

Bipolar Disorder and TreatmentGenetic Associations and Epidemiology

Cited by 363

Prescription Opioid Use and Risk for Major Depressive Disorder and Anxiety and Stress-Related Disorders: A Multivariable Mendelian Randomization Analysis

Rosoff, D. B., Smith, G. D., & Lohoff, F. W. (2021) · JAMA Psychiatry

Opioid Use Disorder TreatmentGenetic Associations and Epidemiology

Cited by 186

Mendelian Randomization Study of PCSK9 and HMG-CoA Reductase Inhibition and Cognitive Function

Rosoff, D. B., Bell, A. S., Jung, J., Wagner, J., Mavromatis, L. A., & Lohoff, F. W. (2022) · Journal of the American College of Cardiology

Lipoproteins and Cardiovascular HealthGenetic Associations and Epidemiology

Cited by 126

Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) in the Brain and Relevance for Neuropsychiatric Disorders

O’Connell, E. M., & Lohoff, F. W. (2020) · Frontiers in Neuroscience

Lipoproteins and Cardiovascular HealthAlzheimer's disease research and treatments

Cited by 93

Time to relapse after 6 and 12 months' treatment of generalized anxiety disorder with venlafaxine extended release

Rickels, K., Etemad, B., Khalid-Khan, S., Lohoff, F. W., Rynn, M. A., & Gallop, R. J. (2010) · Archives of General Psychiatry

Anxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesTreatment of Major Depression

Cited by 63

Genetic association analyses of PDYN polymorphisms with heroin and cocaine addiction

Clarke, T. ‐., Ambrose‐Lanci, L., Ferraro, T. N., Berrettini, W. H., Kampman, K. M., Dackis, C. A., Pettinati, H. M., O’Brien, C. P., Oslin, D. W., & Lohoff, F. W. (2012) · Genes, Brain and Behavior

Neurotransmitter Receptor Influence on BehaviorGenetic Associations and Epidemiology

Cited by 55

Proprotein convertase subtilisin/kexin type 9 (PCSK9) in the central nervous system

Bell, A. S., Wagner, J., Rosoff, D. B., & Lohoff, F. W. (2023) · Neuroscience & Biobehavioral Reviews

Lipoproteins and Cardiovascular HealthAlzheimer's disease research and treatments

Cited by 36

PCSK9 and the Gut-Liver-Brain Axis: A Novel Therapeutic Target for Immune Regulation in Alcohol Use Disorder

Lee, J. S., O’Connell, E. M., Pacher, P., & Lohoff, F. W. (2021) · Journal of Clinical Medicine

Alcohol Consumption and Health EffectsSubstance Abuse Treatment and Outcomes

Cited by 31

Imaging resilience and recovery in alcohol dependence

Charlet, K., Rosenthal, A., Lohoff, F. W., Heinz, A., & Beck, A. (2018) · Addiction

Substance Abuse Treatment and OutcomesNeurotransmitter Receptor Influence on Behavior

Cited by 29

PCSK9 inhibition attenuates alcohol-associated neuronal oxidative stress and cellular injury

Wagner, J., Park, L. M., Mukhopadhyay, P., Matyas, C., Trojnar, E., Damadzic, R., Jung, J., Bell, A. S., Mavromatis, L. A., Hamandi, A. M., et al. (2024) · Brain, Behavior, and Immunity

Neuroinflammation and Neurodegeneration MechanismsAlcohol Consumption and Health Effects

Cited by 26

Targeting Oxidative Stress in Neurodegenerative Disorders: A Novel Role for PCSK9 Inhibition?

Park, L. M., Pacher, P., & Lohoff, F. W. (2024) · ACS Chemical Neuroscience

Alzheimer's disease research and treatmentsNeurological Disease Mechanisms and Treatments

Cited by 16

Multiomic Mendelian Randomization Study Investigating the Impact of PCSK9 and HMGCR Inhibition on Type 2 Diabetes Across Five Populations

Rosoff, D. B., Wagner, J., Jung, J., Pacher, P., Christodoulides, C., Davey Smith, G., Ray, D., & Lohoff, F. W. (2025) · Diabetes

Genetic Associations and EpidemiologyLipoproteins and Cardiovascular Health

Cited by 10