Sun, Junjiang

Optimization of self-complementary AAV vectors for liver-directed expression results in sustained correction of hemophilia B at low vector dose

Wu, Z., Sun, J., Zhang, T., Yin, C., Yin, F., Van Dyke, T., Samulski, R. J., & Monahan, P. E. (2008) · Molecular Therapy

Virus-based gene therapy researchHemophilia Treatment and Research

Cited by 153

Proteasome Inhibitors Enhance Gene Delivery by AAV Virus Vectors Expressing Large Genomes in Hemophilia Mouse and Dog Models: A Strategy for Broad Clinical Application

Monahan, P. E., Lothrop, C. D., Sun, J., Hirsch, M. L., Kafri, T., Kantor, B., Sarkar, R., Tillson, D. M., Elia, J. R., & Samulski, R. J. (2010) · Molecular Therapy

Virus-based gene therapy researchHemophilia Treatment and Research

Cited by 125

Double-stranded RNA innate immune response activation from long-term adeno-associated virus vector transduction

Shao, W., Earley, L. F., Chai, Z., Chen, X., Sun, J., He, T., Deng, M., Hirsch, M. L., Ting, J., Samulski, R. J., et al. (2018) · JCI Insight

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 119

Employing a Gain-of-Function Factor IX Variant R338L to Advance the Efficacy and Safety of Hemophilia B Human Gene Therapy: Preclinical Evaluation Supporting an Ongoing Adeno-Associated Virus Clinical Trial

Monahan, P. E., Sun, J., Gui, T., Hu, G., Hannah, W. B., Wichlan, D. G., Wu, Z., Grieger, J. C., Li, C., Suwanmanee, T., et al. (2015) · Human Gene Therapy

Hemophilia Treatment and ResearchVirus-based gene therapy research

Cited by 108

Cellular immune response to cryptic epitopes during therapeutic gene transfer

Li, C., Goudy, K., Hirsch, M., Asokan, A., Fan, Y., Alexander, J., Sun, J., Monahan, P., Seiber, D., Sidney, J., et al. (2009) · Proceedings of the National Academy of Sciences

Virus-based gene therapy researchImmunotherapy and Immune Responses

Cited by 79

An Observational Study from Long-Term AAV Re-administration in Two Hemophilia Dogs

Sun, J., Shao, W., Chen, X., Merricks, E. P., Wimsey, L., Abajas, Y. L., Niemeyer, G. P., Lothrop, C. D., Monahan, P. E., Samulski, R. J., et al. (2018) · Molecular Therapy - Methods & Clinical Development

Hemophilia Treatment and ResearchVirus-based gene therapy research

Cited by 30

Hemophilia A and B mice, but not VWF−/−mice, display bone defects in congenital development and remodeling after injury

Taves, S., Sun, J., Livingston, E. W., Chen, X., Amiaud, J., Brion, R., Hannah, W. B., Bateman, T. A., Heymann, D., & Monahan, P. E. (2019) · Scientific Reports

Hemophilia Treatment and ResearchBone Metabolism and Diseases

Cited by 26