Bokvist, Krister

LY3298176, a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus: From discovery to clinical proof of concept

Coskun, T., Sloop, K. W., Loghin, C., Alsina-Fernandez, J., Urva, S., Bokvist, K. B., Cui, X., Briere, D. A., Cabrera, O., Roell, W. C., et al. (2018) · Molecular Metabolism

Diabetes Treatment and ManagementDiabetes Management and Research

Cited by 882

Exocytosis elicited by action potentials and voltage‐clamp calcium currents in individual mouse pancreatic B‐cells.

Ammälä, C., Eliasson, L., Bokvist, K., Larsson, O., Ashcroft, F. M., & Rorsman, P. (1993) · The Journal of Physiology

Pancreatic function and diabetesCellular transport and secretion

Cited by 270

Stimulus-secretion coupling in pancreatic β cells

Ashcroft, F. M., Proks, P., Smith, P. A., Ämmälä, C., Bokvist, K., & Rorsman, P. (1994) · Journal of Cellular Biochemistry

Pancreatic function and diabetesIon channel regulation and function

Cited by 255

Neurotransmitter-Induced Inhibition of Exocytosis in Insulin-Secreting β Cells by Activation of Calcineurin

Renström, E., Ding, W.-G., Bokvist, K., & Rorsman, P. (1996) · Neuron

Pancreatic function and diabetesCellular transport and secretion

Cited by 186

A TP-Sensitive K+ Channel–Dependent Regulation of Glucagon Release and Electrical Activity by Glucose in Wild-Type and SUR1−/− Mouse α-Cells

Gromada, J., Ma, X., Høy, M., Bokvist, K., Salehi, A., Berggren, P.-O., & Rorsman, P. (2004) · Diabetes

Pancreatic function and diabetesIon channel regulation and function

Cited by 164

Glucose Stimulates Glucagon Release in Single Rat α-Cells by Mechanisms that Mirror the Stimulus-Secretion Coupling in β-Cells

Olsen, H. L., Theander, S., Bokvist, K., Buschard, K., Wollheim, C. B., & Gromada, J. (2005) · Endocrinology

Pancreatic function and diabetesIon channel regulation and function

Cited by 156

Activation by adrenaline of a low-conductance G protein-dependent K+ channel in mouse pancreatic B cells

Rorsman, P., Bokvist, K., Ämmälä, C., Arkhammar, P., Berggren, P.-O., Larsson, O., & Wåhlander, K. (1991) · Nature

Pancreatic function and diabetesIon channel regulation and function

Cited by 135

Characterisation of sulphonylurea and ATP-regulated K+ channels in rat pancreatic A-cells

Bokvist, K., Olsen, H. L., Høy, M., Gotfredsen, C. F., Holmes, W. F., Buschard, K., Rorsman, P., & Gromada, J. (1999) · Pflügers Archiv

Ion channel regulation and functionPancreatic function and diabetes

Cited by 132

Glucagon-Like Peptide I Increases Cytoplasmic Calcium in Insulin-Secreting βTC3-Cells by Enhancement of Intracellular Calcium Mobilization

Gromada, J., Dissing, S., Bokvist, K., Renström, E., Frøkjær-Jensen, J., Wulff, B. S., & Rorsman, P. (1995) · Diabetes

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 125

Phosphatidylinositol 4-kinase serves as a metabolic sensor and regulates priming of secretory granules in pancreatic β cells

Olsen, H. L., Høy, M., Zhang, W., Bertorello, A. M., Bokvist, K., Capito, K., Efanov, A. M., Meister, B., Thams, P., Yang, S.-N., et al. (2003) · Proceedings of the National Academy of Sciences

Pancreatic function and diabetesCellular transport and secretion

Cited by 101

CaM kinase II‐dependent mobilization of secretory granules underlies acetylcholine‐induced stimulation of exocytosis in mouse pancreatic B‐cells

Gromada, J., Høy, M., Renström, E., Bokvist, K., Eliasson, L., Göpel, S., & Rorsman, P. (1999) · The Journal of Physiology

Pancreatic function and diabetesCellular transport and secretion

Cited by 98

Block of ATP‐regulated and Ca2(+)‐activated K+ channels in mouse pancreatic beta‐cells by external tetraethylammonium and quinine.

Bokvist, K., Rorsman, P., & Smith, P. A. (1990) · The Journal of Physiology

Ion channel regulation and functionPancreatic function and diabetes

Cited by 96

Delayed rectifying and calcium-activated K+ channels and their significance for action potential repolarization in mouse pancreatic beta-cells.

Smith, P. A., Bokvist, K., Arkhammar, P., Berggren, P. O., & Rorsman, P. (1990) · The Journal of general physiology

Ion channel regulation and functionPancreatic function and diabetes

Cited by 86

Stimulation of the KATP channel by ADP and diazoxide requires nucleotide hydrolysis in mouse pancreatic beta‐cells.

Larsson, O., Ammälä, C., Bokvist, K., Fredholm, B., & Rorsman, P. (1993) · The Journal of Physiology

Ion channel regulation and functionPancreatic function and diabetes

Cited by 84

Effects of external tetraethylammonium ions and quinine on delayed rectifying K+ channels in mouse pancreatic beta‐cells.

Bokvist, K., Rorsman, P., & Smith, P. A. (1990) · The Journal of Physiology

Ion channel regulation and functionPancreatic function and diabetes

Cited by 69

Multiple sites of purinergic control of insulin secretion in mouse pancreatic beta-cells.

Poulsen, C. R., Bokvist, K., Olsen, H. L., Høy, M., Capito, K., Gilon, P., & Gromada, J. (1999) · Diabetes

Pancreatic function and diabetesAdenosine and Purinergic Signaling

Cited by 65

Separate processes mediate nucleotide-induced inhibition and stimulation of the ATP-regulated K + -channels in mouse pancreatic β-cells

Bokvist, K. B., Ämmälä, C., Ashcroft, F. M., Berggren, P., Larsson, O., & Rorsman, P. (1991) · Proceedings of the Royal Society of London. Series B: Biological Sciences

Ion channel regulation and functionPancreatic function and diabetes

Cited by 54

Compound exocytosis in voltage-clamped mouse pancreatic β-cells revealed by carbon fibre amperometry

Bokvist, K., Holmqvist, M., Gromada, J., & Rorsman, P. (2000) · Pfl�gers Archiv European Journal of Physiology

Pancreatic function and diabetesCellular transport and secretion

Cited by 48

Tolbutamide stimulates exocytosis of glucagon by inhibition of a mitochondrial‐like ATP‐sensitive K+ (KATP) conductance in rat pancreatic A‐cells

Høy, M., Olsen, H. L., Bokvist, K., Buschard, K., Barg, S., Rorsman, P., & Gromada, J. (2000) · The Journal of Physiology

Pancreatic function and diabetesIon channel regulation and function

Cited by 32

Alpha2-adrenoreceptor stimulation does not inhibit L-type calcium channels in mouse pancreatic β-cells

Bokvist, K., Ämmälä, C., Berggren, P.-O., Rorsman, P., & Wåhlander, K. (1991) · Bioscience Reports

Pancreatic function and diabetesIon channel regulation and function

Cited by 25

Demonstration of a novel apamin-insensitive calcium-activated K+ channel in mouse pancreatic B cells

�mm�l�, C., Bokvist, K., Larsson, O., Berggren, P. O., & Rorsman, P. (1993) · Pfl�gers Archiv European Journal of Physiology

Ion channel regulation and functionPancreatic function and diabetes

Cited by 19