Cheng, Linzhao

A stem cell–like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing

Ohm, J. E., McGarvey, K. M., Yu, X., Cheng, L., Schuebel, K. E., Cope, L., Mohammad, H. P., Chen, W., Daniel, V. C., Yu, W., et al. (2007) · Nature Genetics

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 1,130

Synaptic dysregulation in a human iPS cell model of mental disorders

Wen, Z., Nguyen, H. N., Guo, Z., Lalli, M. A., Wang, X., Su, Y., Kim, N.-S., Yoon, K.-J., Shin, J., Zhang, C., et al. (2014) · Nature

Pluripotent Stem Cells ResearchSchizophrenia research and treatment

Cited by 549

HIF-Dependent Antitumorigenic Effect of Antioxidants In Vivo

Gao, P., Zhang, H., Dinavahi, R., Li, F., Xiang, Y., Raman, V., Bhujwalla, Z. M., Felsher, D. W., Cheng, L., Pevsner, J., et al. (2007) · Cancer Cell

Cancer, Hypoxia, and MetabolismRedox biology and oxidative stress

Cited by 523

Benchmarking spatial and single-cell transcriptomics integration methods for transcript distribution prediction and cell type deconvolution

Li, B., Zhang, W., Guo, C., Xu, H., Li, L., Fang, M., Hu, Y., Zhang, X., Yao, X., Tang, M., et al. (2022) · Nature Methods

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 459

Butyrate greatly enhances derivation of human induced pluripotent stem cells by promoting epigenetic remodeling and the expression of pluripotency-associated genes.

Mali, P., Chou, B.-K., Yen, J., Ye, Z., Zou, J., Dowey, S., Brodsky, R. A., Ohm, J. E., Yu, W., Baylin, S. B., et al. (2010) · Stem Cells

Pluripotent Stem Cells ResearchEpigenetics and DNA Methylation

Cited by 417

Whole-genome sequencing analysis reveals high specificity of CRISPR/Cas9 and TALEN-based genome editing in human iPSCs

Smith, C., Gore, A., Yan, W., Abalde-Atristain, L., Li, Z., He, C., Wang, Y., Brodsky, R. A., Zhang, K., Cheng, L., et al. (2014) · Cell stem cell

CRISPR and Genetic EngineeringPluripotent Stem Cells Research

Cited by 342

Improved Efficiency and Pace of Generating Induced Pluripotent Stem Cells from Human Adult and Fetal Fibroblasts

Mali, P., Ye, Z., Hommond, H. H., Yu, X., Lin, J., Chen, G., Zou, J., & Cheng, L. (2008) · Stem Cells

Pluripotent Stem Cells ResearchMesenchymal stem cell research

Cited by 291

Human iPSC-derived blood-brain barrier microvessels: validation of barrier function and endothelial cell behavior

Linville, R. M., DeStefano, J. G., Sklar, M. B., Xu, Z., Farrell, A. M., Bogorad, M. I., Chu, C., Walczak, P., Cheng, L., Mahairaki, V., et al. (2019) · Biomaterials

Barrier Structure and Function StudiesDrug Transport and Resistance Mechanisms

Cited by 199

The High-Mobility Group A1a/Signal Transducer and Activator of Transcription-3 Axis: An Achilles Heel for Hematopoietic Malignancies?

Hillion, J., Dhara, S., Sumter, T. F., Mukherjee, M., Di Cello, F., Belton, A., Turkson, J., Jaganathan, S., Cheng, L., Ye, Z., et al. (2008) · Cancer Research

Cytokine Signaling Pathways and InteractionsGenomics and Chromatin Dynamics

Cited by 103

Gene and protein expression in human megakaryocytes derived from induced pluripotent stem cells

Kammers, K., Taub, M. A., Mathias, R. A., Yanek, L. R., Kanchan, K., Venkatraman, V., Sundararaman, N., Martin, J., Liu, S., Hoyle, D., et al. (2021) · Journal of Thrombosis and Haemostasis

Platelet Disorders and TreatmentsPluripotent Stem Cells Research

Cited by 10