Clark, Stephen J

Parallel single-cell sequencing links transcriptional and epigenetic heterogeneity

Angermueller, C., Clark, S. J., Lee, H. J., Macaulay, I. C., Teng, M. J., Hu, T. X., Krueger, F., Smallwood, S. A., Ponting, C. P., Voet, T., et al. (2016) · Nature Methods

Epigenetics and DNA MethylationSingle-cell and spatial transcriptomics

Cited by 717

scNMT-seq enables joint profiling of chromatin accessibility DNA methylation and transcription in single cells

Clark, S. J., Argelaguet, R., Kapourani, C.-A., Stubbs, T. M., Lee, H. J., Alda-Catalinas, C., Krueger, F., Sanguinetti, G., Kelsey, G., Marioni, J. C., et al. (2018) · Nature Communications

Epigenetics and DNA MethylationSingle-cell and spatial transcriptomics

Cited by 657

Single-cell epigenomics: powerful new methods for understanding gene regulation and cell identity

Clark, S. J., Lee, H. J., Smallwood, S. A., Kelsey, G., & Reik, W. (2016) · Genome Biology

Single-cell and spatial transcriptomicsEpigenetics and DNA Methylation

Cited by 310

Genome-wide base-resolution mapping of DNA methylation in single cells using single-cell bisulfite sequencing (scBS-seq)

Clark, S. J., Smallwood, S. A., Lee, H. J., Krueger, F., Reik, W., & Kelsey, G. (2017) · Nature Protocols

Epigenetics and DNA MethylationSingle-cell and spatial transcriptomics

Cited by 270

Ageing affects DNA methylation drift and transcriptional cell-to-cell variability in mouse muscle stem cells

Hernando-Herraez, I., Evano, B., Stubbs, T., Commere, P.-H., Jan Bonder, M., Clark, S., Andrews, S., Tajbakhsh, S., & Reik, W. (2019) · Nature Communications

Epigenetics and DNA MethylationSingle-cell and spatial transcriptomics

Cited by 236