Iwata, Masaaki

mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists

Li, N., Lee, B., Liu, R.-J., Banasr, M., Dwyer, J. M., Iwata, M., Li, X.-Y., Aghajanian, G., & Duman, R. S. (2010) · Science

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 2,881

Integrating neuroimmune systems in the neurobiology of depression

Wohleb, E. S., Franklin, T., Iwata, M., & Duman, R. S. (2016) · Nature Reviews Neuroscience

Tryptophan and brain disordersNeuroinflammation and Neurodegeneration Mechanisms

Cited by 668

The inflammasome: Pathways linking psychological stress, depression, and systemic illnesses

Iwata, M., Ota, K. T., & Duman, R. S. (2013) · Brain, Behavior, and Immunity

Tryptophan and brain disordersStress Responses and Cortisol

Cited by 580

Psychological Stress Activates the Inflammasome via Release of Adenosine Triphosphate and Stimulation of the Purinergic Type 2X7 Receptor

Iwata, M., Ota, K. T., Li, X.-Y., Sakaue, F., Li, N., Dutheil, S., Banasr, M., Duric, V., Yamanashi, T., Kaneko, K., et al. (2016) · Biological Psychiatry

Adenosine and Purinergic SignalingTryptophan and brain disorders

Cited by 387

REDD1 is essential for stress-induced synaptic loss and depressive behavior

Ota, K. T., Liu, R.-J., Voleti, B., Maldonado-Aviles, J. G., Duric, V., Iwata, M., Dutheil, S., Duman, C., Boikess, S., Lewis, D. A., et al. (2014) · Nature Medicine

Treatment of Major DepressionStress Responses and Cortisol

Cited by 267

Beta-hydroxybutyrate, an endogenic NLRP3 inflammasome inhibitor, attenuates stress-induced behavioral and inflammatory responses

Yamanashi, T., Iwata, M., Kamiya, N., Tsunetomi, K., Kajitani, N., Wada, N., Iitsuka, T., Yamauchi, T., Miura, A., Pu, S., et al. (2017) · Scientific Reports

Tryptophan and brain disordersTreatment of Major Depression

Cited by 214

Discontinuation of antidepressants after remission with antidepressant medication in major depressive disorder: a systematic review and meta-analysis

Kato, M., Hori, H., Inoue, T., Iga, J., Iwata, M., Inagaki, T., Shinohara, K., Imai, H., Murata, A., Mishima, K., et al. (2021) · Molecular Psychiatry

Treatment of Major DepressionMental Health Treatment and Access

Cited by 152

Prefrontal cortex infusion of beta-hydroxybutyrate, an endogenous NLRP3 inflammasome inhibitor, produces antidepressant-like effects in a rodent model of depression

Kajitani, N., Iwata, M., Miura, A., Tsunetomi, K., Yamanashi, T., Matsuo, R., Nishiguchi, T., Fukuda, S., Nagata, M., Shibushita, M., et al. (2020) · Neuropsychopharmacology Reports

Tryptophan and brain disordersTreatment of Major Depression

Cited by 49