Park, Jong-Wan

Sirtuin 1 Modulates Cellular Responses to Hypoxia by Deacetylating Hypoxia-Inducible Factor 1α

Lim, J.-H., Lee, Y.-M., Chun, Y.-S., Chen, J., Kim, J.-E., & Park, J.-W. (2010) · Molecular Cell

Sirtuins and Resveratrol in MedicineCancer, Hypoxia, and Metabolism

Cited by 758

Jab1 interacts directly with HIF-1α and regulates its stability

Bae, M.-K., Ahn, M.-Y., Jeong, J.-W., Bae, M.-H., Lee, Y. M., Bae, S.-K., Park, J.-W., Kim, K.-R., & Kim, K.-W. (2002) · Journal of Biological Chemistry

Cancer, Hypoxia, and MetabolismKruppel-like factors research

Cited by 196

A novel mode of action of YC-1 in HIF inhibition: stimulation of FIH-dependent p300 dissociation from HIF-1α

Li, S. H., Shin, D. H., Chun, Y.-S., Lee, M. K., Kim, M.-S., & Park, J.-W. (2008) · Molecular Cancer Therapeutics

Cancer, Hypoxia, and MetabolismErythropoietin and Anemia Treatment

Cited by 160

Inhibitory effect of YC-1 on the hypoxic induction of erythropoietin and vascular endothelial growth factor in Hep3B cells11Abbreviations: EPO, erythropoietin; VEGF, vascular endothelial growth factor; HIF, hypoxia-inducible factor; NO, nitric oxide; NOS, nitric oxide synthase; CO, carbon monoxide; sGC, soluble guanylate cyclase; cGMP, cyclic GMP; YC-1, 3-(5′-hydroxymethyl-2′-furyl)-1-benzylindazole; SNP, sodium nitroprusside; ODQ, 1H-(1,2,4)oxadiazole (4,3a)quinoxatin-1-one; MB, methylene blue; NAME, N(G)-nitro-L-arginine methyl ester; RT-PCR, reverse transcription polymerase chain reaction; and EMSA, electrophoretic mobility gel shift.

Chun, Y.-S., Yeo, E.-J., Choi, E., Teng, C.-M., Bae, J.-M., Kim, M.-S., & Park, J.-W. (2001) · Biochemical Pharmacology

Erythropoietin and Anemia TreatmentCancer, Hypoxia, and Metabolism

Cited by 151

ROS mediate the hypoxic repression of the hepcidin gene by inhibiting C/EBPα and STAT-3

Choi, S.-O., Cho, Y.-S., Kim, H.-L., & Park, J.-W. (2007) · Biochemical and Biophysical Research Communications

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 122

Preclinical evaluation of YC-1, a HIF inhibitor, for the prevention of tumor spreading

Shin, D. H., Kim, J.-H., Jung, Y.-J., Kim, K.-E., Jeong, J. M., Chun, Y.-S., & Park, J.-W. (2007) · Cancer Letters

Cancer, Hypoxia, and MetabolismMechanisms of cancer metastasis

Cited by 83

HIF-2α Enhances β-Catenin/TCF-Driven Transcription by Interacting with β-Catenin

Choi, H., Chun, Y.-S., Kim, T.-Y., & Park, J.-W. (2010) · Cancer Research

Wnt/β-catenin signaling in development and cancerCancer, Hypoxia, and Metabolism

Cited by 79