Sadoshima, Junichi

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Acevedo Arozena, A., Adachi, H., Adams, C. M., Adams, P. D., Adeli, K., et al. (2016) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 5,894

Guidelines for the use and interpretation of assays for monitoring autophagy

Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J. A., et al. (2012) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 3,996

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1

Klionsky, D. J., Abdel-Aziz, A. K., Abdelfatah, S., Abdellatif, M., Abdoli, A., Abel, S., Abeliovich, H., Abildgaard, M. H., Abudu, Y. P., Acevedo-Arozena, A., et al. (2021) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 2,897

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

Klionsky, D. J., Abeliovich, H., Agostinis, P., Agrawal, D. K., Aliev, G., Askew, D. S., Baba, M., Baehrecke, E. H., Bahr, B. A., Ballabio, A., et al. (2008) · Autophagy

Autophagy in Disease and TherapyCellular transport and secretion

Cited by 2,230

Autophagy in major human diseases

Klionsky, D. J., Petroni, G., Amaravadi, R. K., Baehrecke, E. H., Ballabio, A., Boya, P., Bravo‐San Pedro, J. M., Cadwell, K., Cecconi, F., Choi, A. M. K., et al. (2021) · The EMBO Journal

Autophagy in Disease and TherapyUbiquitin and proteasome pathways

Cited by 1,585

Distinct Roles of Autophagy in the Heart During Ischemia and Reperfusion: Roles of AMP-Activated Protein Kinase and Beclin 1 in Mediating Autophagy

Matsui, Y., Takagi, H., Qu, X., Abdellatif, M., Sakoda, H., Asano, T., Levine, B., & Sadoshima, J. (2007) · Circulation Research

Autophagy in Disease and TherapyCardiac Ischemia and Reperfusion

Cited by 1,505

Cardioprotection and lifespan extension by the natural polyamine spermidine

Eisenberg, T., Abdellatif, M., Schroeder, S., Primessnig, U., Stekovic, S., Pendl, T., Harger, A., Schipke, J., Zimmermann, A., Schmidt, A., et al. (2016) · Nature Medicine

Polyamine Metabolism and ApplicationsGenetics, Aging, and Longevity in Model Organisms

Cited by 1,168

Sirt1 Regulates Aging and Resistance to Oxidative Stress in the Heart

Alcendor, R. R., Gao, S., Zhai, P., Zablocki, D., Holle, E., Yu, X., Tian, B., Wagner, T., Vatner, S. F., & Sadoshima, J. (2007) · Circulation Research

Sirtuins and Resveratrol in MedicineGenetics, Aging, and Longevity in Model Organisms

Cited by 1,147

NADPH oxidase 4 (Nox4) is a major source of oxidative stress in the failing heart

Kuroda, J., Ago, T., Matsushima, S., Zhai, P., Schneider, M. D., & Sadoshima, J. (2010) · Proceedings of the National Academy of Sciences

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 772

Neuronal SIRT1 Activation as a Novel Mechanism Underlying the Prevention of Alzheimer Disease Amyloid Neuropathology by Calorie Restriction

Qin, W., Yang, T., Ho, L., Zhao, Z., Wang, J., Chen, L., Zhao, W., Thiyagarajan, M., MacGrogan, D., Rodgers, J. T., et al. (2006) · Journal of Biological Chemistry

Alzheimer's disease research and treatmentsSirtuins and Resveratrol in Medicine

Cited by 626

Endogenous Drp1 Mediates Mitochondrial Autophagy and Protects the Heart Against Energy Stress

Ikeda, Y., Shirakabe, A., Maejima, Y., Zhai, P., Sciarretta, S., Toli, J., Nomura, M., Mihara, K., Egashira, K., Ohishi, M., et al. (2015) · Circulation Research

Autophagy in Disease and TherapyMitochondrial Function and Pathology

Cited by 571

The Role of Autophagy in the Heart

Sciarretta, S., Maejima, Y., Zablocki, D., & Sadoshima, J. (2018) · Annual Review of Physiology

Autophagy in Disease and TherapyCardiac Ischemia and Reperfusion

Cited by 547

Upregulation of Nox4 by Hypertrophic Stimuli Promotes Apoptosis and Mitochondrial Dysfunction in Cardiac Myocytes

Ago, T., Kuroda, J., Pain, J., Fu, C., Li, H., & Sadoshima, J. (2010) · Circulation Research

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 506

Mst1 inhibits autophagy by promoting the interaction between Beclin1 and Bcl-2

Maejima, Y., Kyoi, S., Zhai, P., Liu, T., Li, H., Ivessa, A., Sciarretta, S., Del Re, D. P., Zablocki, D. K., Hsu, C.-P., et al. (2013) · Nature Medicine

Autophagy in Disease and TherapyCell death mechanisms and regulation

Cited by 499

Mitophagy is essential for maintaining cardiac function during high fat diet-induced diabetic cardiomyopathy

Tong, M., Saito, T., Zhai, P., Oka, S.-I., Mizushima, W., Nakamura, M., Ikeda, S., Shirakabe, A., & Sadoshima, J. (2019) · Circulation Research

Autophagy in Disease and TherapyCardiovascular Function and Risk Factors

Cited by 498

Nicotinamide Mononucleotide, an Intermediate of NAD+ Synthesis, Protects the Heart from Ischemia and Reperfusion

Yamamoto, T., Byun, J., Zhai, P., Ikeda, Y., Oka, S., & Sadoshima, J. (2014) · PLoS ONE

Cardiac Ischemia and ReperfusionSirtuins and Resveratrol in Medicine

Cited by 305

Enhanced autophagy ameliorates cardiac proteinopathy

Bhuiyan, M. S., Pattison, J. S., Osinska, H., James, J., Gulick, J., McLendon, P. M., Hill, J. A., Sadoshima, J., & Robbins, J. (2013) · Journal of Clinical Investigation

Autophagy in Disease and TherapyHeat shock proteins research

Cited by 298

Rheb is a Critical Regulator of Autophagy During Myocardial Ischemia: Pathophysiological Implications in Obesity and Metabolic Syndrome

Sciarretta, S., Zhai, P., Shao, D., Maejima, Y., Robbins, J., Volpe, M., Condorelli, G., & Sadoshima, J. (2012) · Circulation

Autophagy in Disease and TherapyCardiac Ischemia and Reperfusion

Cited by 292

A redox-dependent mechanism for regulation of AMPK activation by thioredoxin1 during energy starvation

Shao, D., Oka, S.-I., Liu, T., Zhai, P., Ago, T., Sciarretta, S., Li, H., & Sadoshima, J. (2014) · Cell Metabolism

Metabolism, Diabetes, and CancerRedox biology and oxidative stress

Cited by 252

Yes-associated Protein Isoform 1 (Yap1) Promotes Cardiomyocyte Survival and Growth to Protect against Myocardial Ischemic Injury

Del Re, D. P., Yang, Y., Nakano, N., Cho, J., Zhai, P., Yamamoto, T., Zhang, N., Yabuta, N., Nojima, H., Pan, D., et al. (2013) · Journal of Biological Chemistry

Congenital heart defects researchHippo pathway signaling and YAP/TAZ

Cited by 249

Differential Roles of GSK-3β During Myocardial Ischemia and Ischemia/Reperfusion

Zhai, P., Sciarretta, S., Galeotti, J., Volpe, M., & Sadoshima, J. (2011) · Circulation Research

Cardiac Ischemia and ReperfusionAutophagy in Disease and Therapy

Cited by 218

Increased Oxidative Stress in the Nucleus Caused by Nox4 Mediates Oxidation of HDAC4 and Cardiac Hypertrophy

Matsushima, S., Kuroda, J., Ago, T., Zhai, P., Park, J. Y., Xie, L.-H., Tian, B., & Sadoshima, J. (2013) · Circulation Research

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

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Upregulation of Rubicon promotes autosis during myocardial ischemia/reperfusion injury

Nah, J., Zhai, P., Huang, C.-Y., Fernández, Á. F., Mareedu, S., Levine, B., & Sadoshima, J. (2020) · Journal of Clinical Investigation

Autophagy in Disease and TherapyCardiac Ischemia and Reperfusion

Cited by 150

Skeletal muscle NOX4 is required for adaptive responses that prevent insulin resistance

Xirouchaki, C. E., Jia, Y., McGrath, M. J., Greatorex, S., Tran, M., Merry, T. L., Hong, D., Eramo, M. J., Broome, S. C., Woodhead, J. S. T., et al. (2021) · Science Advances

Redox biology and oxidative stressExercise and Physiological Responses

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