Zhang, Jianming

An ATP-competitive Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-resistant Functions of mTORC1

Thoreen, C. C., Kang, S. A., Chang, J. W., Liu, Q., Zhang, J., Gao, Y., Reichling, L. J., Sim, T., Sabatini, D. M., & Gray, N. S. (2009) · Journal of Biological Chemistry

PI3K/AKT/mTOR signaling in cancerAutophagy in Disease and Therapy

Cited by 1,803

Construction of a human cell landscape at single-cell level

Han, X., Zhou, Z., Fei, L., Sun, H., Wang, R., Chen, Y., Chen, H., Wang, J., Tang, H., Ge, W., et al. (2020) · Nature

Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies

Cited by 1,087

Activating mutations in ALK provide a therapeutic target in neuroblastoma

George, R. E., Sanda, T., Hanna, M., Fröhling, S., II, W. L., Zhang, J., Ahn, Y., Zhou, W., London, W. B., McGrady, P., et al. (2008) · Nature

Neuroblastoma Research and TreatmentsNeurofibromatosis and Schwannoma Cases

Cited by 893

Discovery of 1-(4-(4-Propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1 H)-one as a Highly Potent, Selective Mammalian Target of Rapamycin (mTOR) Inhibitor for the Treatment of Cancer

Liu, Q., Chang, J. W., Wang, J., Kang, S. A., Thoreen, C. C., Markhard, A., Hur, W., Zhang, J., Sim, T., Sabatini, D. M., et al. (2010) · Journal of Medicinal Chemistry

PI3K/AKT/mTOR signaling in cancerHeterocyclic Compound Synthesis and Bioactivity

Cited by 257

Small-Molecule Reactivation of Mutant p53 to Wild-Type-like p53 through the p53-Hsp40 Regulatory Axis

Hiraki, M., Hwang, S.-Y., Cao, S., Ramadhar, T. R., Byun, S., Yoon, K. W., Lee, J. H., Chu, K., Gurkar, A. U., Kolev, V., et al. (2015) · Chemistry & Biology

Cancer-related Molecular PathwaysHeat shock proteins research

Cited by 81

The Risk of Metabolic Syndrome in Patients with Rheumatoid Arthritis: A Meta-Analysis of Observational Studies

Zhang, J., Fu, L., Shi, J., Chen, X., Li, Y., Ma, B., & Zhang, Y. (2013) · PLoS ONE

Rheumatoid Arthritis Research and TherapiesDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 81

Interferon-α2b gene-modified human bone marrow mesenchymal stem cells inhibit hepatocellular carcinoma by reducing the Notch1 levels

Su, Y., Cheng, R., Zhang, J., Qian, J., Diao, C., Ran, J., Zhang, H., & Li, L. (2015) · Life Sciences

Mesenchymal stem cell researchBacterial Cancer Therapy

Cited by 25