Wei, Lai

Generation of pathogenic TH17 cells in the absence of TGF-β signalling

Ghoreschi, K., Laurence, A., Yang, X.-P., Tato, C. M., McGeachy, M. J., Konkel, J. E., Ramos, H. L., Wei, L., Davidson, T. S., Bouladoux, N., et al. (2010) · Nature

Psoriasis: Treatment and PathogenesisT-cell and B-cell Immunology

Cited by 1,388

Global Mapping of H3K4me3 and H3K27me3 Reveals Specificity and Plasticity in Lineage Fate Determination of Differentiating CD4+ T Cells

Wei, G., Wei, L., Zhu, J., Zang, C., Hu-Li, J., Yao, Z., Cui, K., Kanno, Y., Roh, T.-Y., Watford, W. T., et al. (2009) · Immunity

T-cell and B-cell ImmunologyGenomics and Chromatin Dynamics

Cited by 1,152

COVID-19 immune features revealed by a large-scale single-cell transcriptome atlas

Ren, X., Wen, W., Fan, X., Hou, W., Su, B., Cai, P., Li, J., Liu, Y., Tang, F., Zhang, F., et al. (2021) · Cell

Single-cell and spatial transcriptomicsCOVID-19 Clinical Research Studies

Cited by 865

Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5

Yang, X.-P., Ghoreschi, K., Steward-Tharp, S. M., Rodriguez-Canales, J., Zhu, J., Grainger, J. R., Hirahara, K., Sun, H.-W., Wei, L., Vahedi, G., et al. (2011) · Nature Immunology

Psoriasis: Treatment and PathogenesisT-cell and B-cell Immunology

Cited by 583

Genome-wide CRISPR/Cas9 library screening identified PHGDH as a critical driver for Sorafenib resistance in HCC

Wei, L., Lee, D., Law, C.-T., Zhang, M. S., Shen, J., Chin, D. W.-C., Zhang, A., Tsang, F. H.-C., Wong, C. L.-S., Ng, I. O.-L., et al. (2019) · Nature Communications

Cancer, Hypoxia, and MetabolismHepatocellular Carcinoma Treatment and Prognosis

Cited by 428

The methylcytosine dioxygenase Tet2 promotes DNA demethylation and activation of cytokine gene expression in T cells

Ichiyama, K., Chen, T., Wang, X., Yan, X., Kim, B.-S., Tanaka, S., Ndiaye-Lobry, D., Deng, Y., Zou, Y., Zheng, P., et al. (2015) · Immunity

Epigenetics and DNA MethylationT-cell and B-cell Immunology

Cited by 327

FBXO38 mediates PD-1 ubiquitination and regulates anti-tumour immunity of T cells

Meng, X., Liu, X., Guo, X., Jiang, S., Chen, T., Hu, Z., Liu, H., Bai, Y., Xue, M., Hu, R., et al. (2018) · Nature

Cancer Immunotherapy and BiomarkersT-cell and B-cell Immunology

Cited by 303

Hematopoietic Progenitor Kinase1 (HPK1) Mediates T Cell Dysfunction and Is a Druggable Target for T Cell-Based Immunotherapies

Si, J., Shi, X., Sun, S., Zou, B., Li, Y., An, D., Lin, X., Gao, Y., Long, F., Pang, B., et al. (2020) · Cancer Cell

Cancer Immunotherapy and BiomarkersT-cell and B-cell Immunology

Cited by 209

Hypomethylation of the IL17RC Promoter Associates with Age-Related Macular Degeneration

Wei, L., Liu, B., Tuo, J., Shen, D., Chen, P., Li, Z., Liu, X., Ni, J., Dagur, P., Sen, H. N., et al. (2012) · Cell Reports

Retinal Diseases and TreatmentsEpigenetics and DNA Methylation

Cited by 167

Complement Component C5a Promotes Expression of IL-22 and IL-17 from Human T Cells and Its Implication in Age-Related Macular Degeneration

Liu, B., Wei, L., Meyerle, C., Tuo, J., Sen, H. N., Li, Z., Chakrabarty, S., Agron, E., Chan, C.-C., Klein, M. L., et al. (2011) · Journal of Translational Medicine

Complement system in diseasesRetinal Diseases and Treatments

Cited by 164

Tumor Progression Locus 2 (Map3k8) Is Critical for Host Defense against Listeria monocytogenes and IL-1β Production

Mielke, L. A., Elkins, K. L., Wei, L., Starr, R., Tsichlis, P. N., O'Shea, J. J., & Watford, W. T. (2009) · The Journal of Immunology

Immune Response and InflammationImmune responses and vaccinations

Cited by 98

Chronic stress-induced depression requires the recruitment of peripheral Th17 cells into the brain

Peng, Z., Peng, S., Lin, K., Zhao, B., Wei, L., Tuo, Q., Liao, D., Yuan, T., & Shi, Z. (2022) · Journal of Neuroinflammation

Tryptophan and brain disordersStress Responses and Cortisol

Cited by 95

Signal transduction and Th17 cell differentiation

O'Shea, J. J., Steward-Tharp, S. M., Laurence, A., Watford, W. T., Wei, L., Adamson, A. S., & Fan, S. (2009) · Microbes and Infection

Psoriasis: Treatment and PathogenesisT-cell and B-cell Immunology

Cited by 73