Yao, Hui

Antibody Conjugation of a Chimeric BET Degrader Enables in vivo Activity

Pillow, T. H., Adhikari, P., Blake, R. A., Chen, J., Del Rosario, G., Deshmukh, G., Figueroa, I., Gascoigne, K. E., Kamath, A. V., Kaufman, S., et al. (2020) · ChemMedChem

Protein Degradation and InhibitorsChemical Synthesis and Analysis

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Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 2: Improvement of In Vitro Antiproliferation Activity and In Vivo Antitumor Efficacy

Dragovich, P. S., Pillow, T. H., Blake, R. A., Sadowsky, J. D., Adaligil, E., Adhikari, P., Chen, J., Corr, N., dela Cruz-Chuh, J., Del Rosario, G., et al. (2021) · Journal of Medicinal Chemistry

Protein Degradation and InhibitorsMonoclonal and Polyclonal Antibodies Research

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Antibody-mediated delivery of chimeric protein degraders which target estrogen receptor alpha (ERα)

Dragovich, P. S., Adhikari, P., Blake, R. A., Blaquiere, N., Chen, J., Cheng, Y.-X., den Besten, W., Han, J., Hartman, S. J., He, J., et al. (2020) · Bioorganic & Medicinal Chemistry Letters

Protein Degradation and InhibitorsMonoclonal and Polyclonal Antibodies Research

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HNF4α is a therapeutic target that links AMPK to WNT signalling in early-stage gastric cancer

Chang, H. R., Nam, S., Kook, M.-C., Kim, K.-T., Liu, X., Yao, H., Jung, H. R., Lemos, R., Seo, H. H., Park, H. S., et al. (2016) · Gut

Gastric Cancer Management and OutcomesMetabolism, Diabetes, and Cancer

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BAP1 inhibits the ER stress gene regulatory network and modulates metabolic stress response

Dai, F., Lee, H., Zhang, Y., Zhuang, L., Yao, H., Xi, Y., Xiao, Z.-D., You, M. J., Li, W., Su, X., et al. (2017) · Proceedings of the National Academy of Sciences

Endoplasmic Reticulum Stress and DiseaseGenomics, phytochemicals, and oxidative stress

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