Li, Feiran

Deep learning-based kcat prediction enables improved enzyme-constrained model reconstruction

Li, F., Yuan, L., Lu, H., Li, G., Chen, Y., Engqvist, M. K. M., Kerkhoven, E. J., & Nielsen, J. (2022) · Nature Catalysis

Microbial Metabolic Engineering and BioproductionBioinformatics and Genomic Networks

Cited by 466

Genome scale modeling of the protein secretory pathway reveals novel targets for improved recombinant protein production in yeast

Li, F., Chen, Y., Qi, Q., Wang, Y., Yuan, L., Huang, M., Elsemman, I. E., Feizi, A., Kerkhoven, E. J., & Nielsen, J. (2021) · Nature Communications

Microbial Metabolic Engineering and BioproductionFungal and yeast genetics research

Cited by 91

Yeast optimizes metal utilization based on metabolic network and enzyme kinetics

Chen, Y., Li, F., Mao, J., Chen, Y., & Nielsen, J. (2021) · Proceedings of the National Academy of Sciences

Microbial Metabolic Engineering and BioproductionGene Regulatory Network Analysis

Cited by 46

Yeast metabolic innovations emerged via expanded metabolic network and gene positive selection

Lu, H., Li, F., Yuan, L., Domenzain, I., Yu, R., Wang, H., Li, G., Chen, Y., Ji, B., Kerkhoven, E. J., et al. (2021) · Molecular Systems Biology

Microbial Metabolic Engineering and BioproductionFungal and yeast genetics research

Cited by 44

The Role of Metabolism in Shaping Enzyme Structures Over 400 Million Years of Evolution

Lemke, O., Heineike, B. M., Viknander, S., Cohen, N., Steenwyk, J. L., Spranger, L., Li, F., Agostini, F., Lee, C. T., Aulakh, S. K., et al. (2024) · Nature

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 28