Li, Yue-Ming

Photoactivated γ-secretase inhibitors directed to the active site covalently label presenilin 1

Li, Y.-M., Xu, M., Lai, M.-T., Huang, Q., Castro, J. L., DiMuzio-Mower, J., Harrison, T., Lellis, C., Nadin, A., Neduvelil, J. G., et al. (2000) · Nature

Alzheimer's disease research and treatmentsProtease and Inhibitor Mechanisms

Cited by 866

The innate immunity protein IFITM3 modulates γ-secretase in Alzheimer’s disease

Hur, J.-Y., Frost, G. R., Wu, X., Crump, C., Pan, S. J., Wong, E., Barros, M., Li, T., Nie, P., Zhai, Y., et al. (2020) · Nature

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 382

Hypoxia Inducible Factor-1α binds and activates γ-secretase for Aβ production under hypoxia and cerebral hypoperfusion

Alexander, C., Li, T., Hattori, Y., Chiu, D., Frost, G. R., Jonas, L., Liu, C., Anderson, C. J., Wong, E., Park, L., et al. (2022) · Molecular Psychiatry

Alzheimer's disease research and treatmentsNeurological Disease Mechanisms and Treatments

Cited by 64

Turning the tide on Alzheimer’s disease: modulation of γ-secretase

Luo, J. E., & Li, Y.-M. (2022) · Cell & Bioscience

Alzheimer's disease research and treatmentsCholinesterase and Neurodegenerative Diseases

Cited by 59

γ-Secretase fanning the fire of innate immunity

Liu, C., Nikain, C., & Li, Y.-M. (2023) · Biochemical Society Transactions

Immune Response and InflammationAlzheimer's disease research and treatments

Cited by 4