Mead, Emma

TREM2/PLCγ2 signalling in immune cells: function, structural insight, and potential therapeutic modulation

Magno, L., Bunney, T. D., Mead, E., Svensson, F., & Bictash, M. N. (2021) · Molecular Neurodegeneration

Neuroinflammation and Neurodegeneration MechanismsInflammasome and immune disorders

Cited by 64

TREM2 Alzheimer’s variant R47H causes similar transcriptional dysregulation to knockout, yet only subtle functional phenotypes in human iPSC-derived macrophages

Hall-Roberts, H., Agarwal, D., Obst, J., Smith, T. B., Monzón-Sandoval, J., Di Daniel, E., Webber, C., James, W. S., Mead, E., Davis, J. B., et al. (2020) · Alzheimer's Research & Therapy

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 62

PLCγ2 regulates TREM2 signalling and integrin-mediated adhesion and migration of human iPSC-derived macrophages

Obst, J., Hall-Roberts, H. L., Smith, T. B., Kreuzer, M., Magno, L., Di Daniel, E., Davis, J. B., & Mead, E. (2021) · Scientific Reports

Neuroinflammation and Neurodegeneration MechanismsPhagocytosis and Immune Regulation

Cited by 36