Huber, Robert

Mechanism of inhibition of the human matrix metalloproteinase stromelysin-1 by TIMP-1.

Gomis-R¨th, F.-X., Maskos, K., Betz, M., Bergner, A., Huber, R., Suzuki, K., Yoshida, N., Nagase, H., Brew, K., Bourenkov, G. P., et al. (1997) · Nature

Protease and Inhibitor MechanismsBlood Coagulation and Thrombosis Mechanisms

Cited by 619

Crystal Structure of Epoxomicin:20S Proteasome Reveals a Molecular Basis for Selectivity of α‘,β‘-Epoxyketone Proteasome Inhibitors

Groll, M., Kim, K. B., Kairies, N., Huber, R., & Crews, C. M. (2000) · Journal of the American Chemical Society

Ubiquitin and proteasome pathwaysEnzyme Structure and Function

Cited by 304

Crystal structure of protoporphyrinogen IX oxidase: a key enzyme in haem and chlorophyll biosynthesis

Koch, M., Breithaupt, C., Kiefersauer, R., Freigang, J., Huber, R., & Messerschmidt, A. (2004) · The EMBO Journal

Porphyrin Metabolism and DisordersPorphyrin and Phthalocyanine Chemistry

Cited by 299

Crystal structure of the first dissimilatory nitrate reductase at 1.9 Å solved by MAD methods

Dias, J. M., Than, M. E., Humm, A., Huber, R., Bourenkov, G. P., Bartunik, H. D., Bursakov, S., Calvete, J., Caldeira, J., Carneiro, C., et al. (1999) · Structure

Metalloenzymes and iron-sulfur proteinsEnzyme Structure and Function

Cited by 286

Structure of the Stapled p53 Peptide Bound to Mdm2

Baek, S., Kutchukian, P. S., Verdine, G. L., Huber, R., Holak, T. A., Lee, K. W., & Popowicz, G. M. (2012) · Journal of the American Chemical Society

Cancer-related Molecular PathwaysChemical Synthesis and Analysis

Cited by 259

A structure-based catalytic mechanism for the xanthine oxidase family of molybdenum enzymes

Huber, R., Hof, P., Duarte, R. O., Moura, J. J., Moura, I., Liu, M. Y., LeGall, J., Hille, R., Archer, M., & Romão, M. J. (1996) · Proceedings of the National Academy of Sciences

Metalloenzymes and iron-sulfur proteinsEnzyme Structure and Function

Cited by 242

Zur Chemie des Ecdysons, VII: Die Kristall- und Molekülstrukturanalyse des Insektenverpuppungshormons ecdyson mit der automatisierten Faltmolekülmethode

Huber, R., & Hoppe, W. (1965) · Chemische Berichte

Steroid Chemistry and BiochemistryCrystal structures of chemical compounds

Cited by 219

Cerebral small vessel disease-related protease HtrA1 processes latent TGF-β binding protein 1 and facilitates TGF-β signaling

Beaufort, N., Scharrer, E., Kremmer, E., Lux, V., Ehrmann, M., Huber, R., Houlden, H., Werring, D., Haffner, C., & Dichgans, M. (2014) · Proceedings of the National Academy of Sciences

TGF-β signaling in diseasesCerebrovascular and genetic disorders

Cited by 145