Fischer, M. Dominik

Immune responses to retinal gene therapy using adeno-associated viral vectors – implications for treatment success and safety

Bucher, K., Rodríguez-Bocanegra, E., Dauletbekov, D., & Fischer, M. D. (2021) · Progress in Retinal and Eye Research

Virus-based gene therapy researchRetinal Development and Disorders

Cited by 242

Efficacy and Safety of Retinal Gene Therapy Using Adeno-Associated Virus Vector for Patients With Choroideremia: A Randomized Clinical Trial

Fischer, M. D., Ochakovski, G. A., Beier, B., Seitz, I. P., Vaheb, Y., Kortuem, C., Reichel, F. F. L., Kuehlewein, L., Kahle, N. A., Peters, T., et al. (2019) · JAMA Ophthalmology

Retinal Development and DisordersVirus-based gene therapy research

Cited by 92

Targeting Resistance against the MDM2 Inhibitor RG7388 in Glioblastoma Cells by the MEK Inhibitor Trametinib

Berberich, A., Kessler, T., Thomé, C. M., Pusch, S., Hielscher, T., Sahm, F., Oezen, I., Schmitt, L.-M., Ciprut, S., Hucke, N., et al. (2019) · Clinical Cancer Research

Glioma Diagnosis and TreatmentCancer-related Molecular Pathways

Cited by 75

Subretinal timrepigene emparvovec in adult men with choroideremia: a randomized phase 3 trial

MacLaren, R. E., Fischer, M. D., Gow, J. A., Lam, B. L., Sankila, E.-M. K., Girach, A., Panda, S., Yoon, D., Zhao, G., & Pennesi, M. E. (2023) · Nature Medicine

Retinal Development and DisordersVirus-based gene therapy research

Cited by 58

Dose-dependent progression of chorioretinal atrophy at the injection site after subretinal injection of rAAV2/8 in nonhuman primates

Seitz, I. P., Wozar, F., Ochakovski, G. A., Reichel, F. F., Gelisken, F., Bartz-Schmidt, K. U., Peters, T., & Fischer, M. D. (2024) · Ophthalmology Science

Retinal Development and DisordersVirus-based gene therapy research

Cited by 16

An open-label phase II study assessing the safety of bilateral, sequential administration of retinal gene therapy in participants with choroideremia: the GEMINI study

MacLaren, R. E., Audo, I., Fischer, M. D., Huckfeldt, R. M., Lam, B. L., Pennesi, M. E., Sisk, R., Gow, J. A., Li, J., Zhu, K., et al. (2024) · Human Gene Therapy

Retinal Development and DisordersVirus-based gene therapy research

Cited by 15