Schmidt, Paul J.

Metal ion chaperone function of the soluble Cu(I) receptor Atx1.

Pufahl, R. A., Singer, C. P., Peariso, K. L., Lin, S.-J., Schmidt, P. J., Fahrni, C. J., Culotta, V. C., Penner-Hahn, J. E., & O'Halloran, T. V. (1997) · Science

Trace Elements in HealthMetal-Catalyzed Oxygenation Mechanisms

Cited by 691

Physiologic Expression of Sf3b1(K700E) Causes Impaired Erythropoiesis, Aberrant Splicing, and Sensitivity to Therapeutic Spliceosome Modulation

Obeng, E. A., Chappell, R. J., Seiler, M., Chen, M. C., Campagna, D. R., Schmidt, P. J., Schneider, R. K., Lord, A. M., Wang, L., Gambe, R. G., et al. (2016) · Cancer Cell

RNA Research and SplicingAcute Myeloid Leukemia Research

Cited by 380

The Transferrin Receptor Modulates Hfe-Dependent Regulation of Hepcidin Expression

Schmidt, P. J., Toran, P. T., Giannetti, A. M., Bjorkman, P. J., & Andrews, N. C. (2008) · Cell Metabolism

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 345

Mutations in mitochondrial carrier family gene SLC25A38 cause nonsyndromic autosomal recessive congenital sideroblastic anemia

Guernsey, D. L., Jiang, H., Campagna, D. R., Evans, S. C., Ferguson, M., Kellogg, M. D., Lachance, M., Matsuoka, M., Nightingale, M., Rideout, A., et al. (2009) · Nature Genetics

Iron Metabolism and DisordersHemoglobinopathies and Related Disorders

Cited by 244

The IRP1-HIF-2α Axis Coordinates Iron and Oxygen Sensing with Erythropoiesis and Iron Absorption

Anderson, S. A., Nizzi, C. P., Chang, Y.-I., Deck, K. M., Schmidt, P. J., Galy, B., Damnernsawad, A., Broman, A. T., Kendziorski, C., Hentze, M. W., et al. (2013) · Cell Metabolism

Iron Metabolism and DisordersErythropoietin and Anemia Treatment

Cited by 211

An RNAi therapeutic targeting Tmprss6 decreases iron overload in Hfe−/− mice and ameliorates anemia and iron overload in murine β-thalassemia intermedia

Schmidt, P. J., Toudjarska, I., Sendamarai, A. K., Racie, T., Milstein, S., Bettencourt, B. R., Hettinger, J., Bumcrot, D., & Fleming, M. D. (2013) · Blood

Iron Metabolism and DisordersHemoglobinopathies and Related Disorders

Cited by 204

BMP6 treatment compensates for the molecular defect and ameliorates hemochromatosis in Hfe knockout mice

Corradini, E., Schmidt, P. J., Meynard, D., Garuti, C., Montosi, G., Chen, S., Vukicevic, S., Pietrangelo, A., Lin, H. Y., & Babitt, J. L. (2010) · Gastroenterology

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 109

Combination therapy with a T mprss6 RNA i‐therapeutic and the oral iron chelator deferiprone additively diminishes secondary iron overload in a mouse model of β‐thalassemia intermedia

Schmidt, P. J., Racie, T., Westerman, M., Fitzgerald, K., Butler, J. S., & Fleming, M. D. (2015) · American Journal of Hematology

Iron Metabolism and DisordersHemoglobinopathies and Related Disorders

Cited by 77

Congenital sideroblastic anemia due to mutations in the mitochondrial HSP70 homologue HSPA9

Schmitz-Abe, K., Ciesielski, S. J., Schmidt, P. J., Campagna, D. R., Rahimov, F., Schilke, B. A., Cuijpers, M., Rieneck, K., Lausen, B., Linenberger, M. L., et al. (2015) · Blood

Iron Metabolism and DisordersHemoglobinopathies and Related Disorders

Cited by 75