Lamb, John

Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease

Zhang, B., Gaiteri, C., Bodea, L.-G., Wang, Z., McElwee, J., Podtelezhnikov, A. A., Zhang, C., Xie, T., Tran, L., Dobrin, R., et al. (2013) · Cell

Alzheimer's disease research and treatmentsBioinformatics and Genomic Networks

Cited by 1,657

Genetics of gene expression and its effect on disease

Emilsson, V., Thorleifsson, G., Zhang, B., Leonardson, A. S., Zink, F., Zhu, J., Carlson, S., Helgason, A., Walters, G. B., Gunnarsdottir, S., et al. (2008) · Nature

Genetic Associations and EpidemiologyAdipokines, Inflammation, and Metabolic Diseases

Cited by 1,296

An integrative genomics approach to infer causal associations between gene expression and disease

Schadt, E. E., Lamb, J., Yang, X., Zhu, J., Edwards, S., GuhaThakurta, D., Sieberts, S. K., Monks, S., Reitman, M., Zhang, C., et al. (2005) · Nature Genetics

Genetic Associations and EpidemiologyBioinformatics and Genomic Networks

Cited by 1,043

Variations in DNA elucidate molecular networks that cause disease

Chen, Y., Zhu, J., Lum, P. Y., Yang, X., Pinto, S., MacNeil, D. J., Zhang, C., Lamb, J., Edwards, S., Sieberts, S. K., et al. (2008) · Nature

Bioinformatics and Genomic NetworksNutrition, Genetics, and Disease

Cited by 887

Co-regulatory networks of human serum proteins link genetics to disease

Emilsson, V., Ilkov, M., Lamb, J. R., Finkel, N., Gudmundsson, E. F., Pitts, R., Hoover, H., Gudmundsdottir, V., Horman, S. R., Aspelund, T., et al. (2018) · Science

Bioinformatics and Genomic NetworksGenetic Associations and Epidemiology

Cited by 680

Validation of candidate causal genes for obesity that affect shared metabolic pathways and networks

Yang, X., Deignan, J. L., Qi, H., Zhu, J., Qian, S., Zhong, J., Torosyan, G., Majid, S., Falkard, B., Kleinhanz, R. R., et al. (2009) · Nature Genetics

Bioinformatics and Genomic NetworksGenetic Associations and Epidemiology

Cited by 288

In vivo discovery of immunotherapy targets in the tumour microenvironment

Zhou, P., Shaffer, D. R., Alvarez Arias, D. A., Nakazaki, Y., Pos, W., Torres, A. J., Cremasco, V., Dougan, S. K., Cowley, G. S., Elpek, K., et al. (2014) · Nature

Cancer Immunotherapy and BiomarkersT-cell and B-cell Immunology

Cited by 237

Diet Induction of Monocyte Chemoattractant Protein‐1 and its Impact on Obesity

Chen, A., Mumick, S., Zhang, C., Lamb, J., Dai, H., Weingarth, D., Mudgett, J., Chen, H., MacNeil, D. J., Reitman, M. L., et al. (2005) · Obesity Research

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 231

An integrative genomics approach to the reconstruction of gene networks in segregating populations

Zhu, J., Lum, P. Y., Lamb, J., GuhaThakurta, D., Edwards, S. W., Thieringer, R., Berger, J. P., Wu, M. S., Thompson, J., Sachs, A. B., et al. (2004) · Cytogenetic and Genome Research

Gene Regulatory Network AnalysisBioinformatics and Genomic Networks

Cited by 221

Common dysregulation network in the human prefrontal cortex underlies two neurodegenerative diseases

Narayanan, M., Huynh, J. L., Wang, K., Yang, X., Yoo, S., McElwee, J., Zhang, B., Zhang, C., Lamb, J. R., Xie, T., et al. (2014) · Molecular Systems Biology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 208

Diurnal variation of the human adipose transcriptome and the link to metabolic disease

Loboda, A., Kraft, W. K., Fine, B., Joseph, J., Nebozhyn, M., Zhang, C., He, Y., Yang, X., Wright, C., Morris, M., et al. (2009) · BMC Medical Genomics

Circadian rhythm and melatoninAdipose Tissue and Metabolism

Cited by 124

Guide Swap enables genome-scale pooled CRISPR-Cas9 screening in human primary cells

Ting, P. Y., Parker, A. E., Lee, J. S., Trussell, C., Sharif, O., Luna, F., Federe, G., Barnes, S. W., Walker, J. R., Vance, J., et al. (2018) · Nature Methods

CRISPR and Genetic EngineeringRNA Interference and Gene Delivery

Cited by 80

UV mutation spectra in cell lines from patients with Cockayne's syndrome and ataxia telangiectasia, using the shuttle vector pZ189

Muriel, W. J., Lamb, J. R., & Lehmann, A. R. (1991) · Mutation Research/DNA Repair

DNA Repair MechanismsCarcinogens and Genotoxicity Assessment

Cited by 21