Delpech, Jean-Christophe

Plaque associated microglia hyper-secrete extracellular vesicles and accelerate tau propagation in a humanized APP mouse model

Clayton, K., Delpech, J. C., Herron, S., Iwahara, N., Ericsson, M., Saito, T., Saido, T. C., Ikezu, S., & Ikezu, T. (2021) · Molecular Neurodegeneration

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 245

Neuroimmune Crosstalk through Extracellular Vesicles in Health and Disease

Delpech, J.-C., Herron, S., Botros, M. B., & Ikezu, T. (2019) · Trends in Neurosciences

Extracellular vesicles in diseaseNeuroinflammation and Neurodegeneration Mechanisms

Cited by 193

Early life stress perturbs the maturation of microglia in the developing hippocampus

Delpech, J.-C., Wei, L., Hao, J., Yu, X., Madore, C., Butovsky, O., & Kaffman, A. (2016) · Brain Behavior and Immunity

Neuroinflammation and Neurodegeneration MechanismsStress Responses and Cortisol

Cited by 193

P2RX7 inhibitor suppresses exosome secretion and disease phenotype in P301S tau transgenic mice

Ruan, Z., Delpech, J.-C., Venkatesan Kalavai, S., Van Enoo, A. A., Hu, J., Ikezu, S., & Ikezu, T. (2020) · Molecular Neurodegeneration

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 150

Identification of a protective microglial state mediated by miR-155 and interferon-γ signaling in a mouse model of Alzheimer’s disease

Yin, Z., Herron, S., Silveira, S., Kleemann, K., Gauthier, C., Mallah, D., Cheng, Y., Margeta, M. A., Pitts, K. M., Barry, J.-L., et al. (2023) · Nature Neuroscience

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 120