Sacchettini, James C.

PHENIX : building new software for automated crystallographic structure determination

Adams, P. D., Grosse-Kunstleve, R. W., Hung, L.-W., Ioerger, T. R., McCoy, A. J., Moriarty, N. W., Read, R. J., Sacchettini, J. C., Sauter, N. K., & Terwilliger, T. C. (2002) · Acta Crystallographica Section D Biological Crystallography

Enzyme Structure and FunctionCrystal structures of chemical compounds

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Sterilization of granulomas is common in active and latent tuberculosis despite within-host variability in bacterial killing

Lin, P. L., Ford, C. B., Coleman, M. T., Myers, A. J., Gawande, R., Ioerger, T., Sacchettini, J., Fortune, S. M., & Flynn, J. L. (2014) · Nature Medicine

Tuberculosis Research and EpidemiologyImmune responses and vaccinations

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Use of whole genome sequencing to estimate the mutation rate of Mycobacterium tuberculosis during latent infection

Ford, C. B., Lin, P. L., Chase, M. R., Shah, R. R., Iartchouk, O., Galagan, J., Mohaideen, N., Ioerger, T. R., Sacchettini, J. C., Lipsitch, M., et al. (2011) · Nature Genetics

Tuberculosis Research and EpidemiologyInfectious Diseases and Tuberculosis

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Tryptophan Biosynthesis Protects Mycobacteria from CD4 T-Cell-Mediated Killing

Zhang, Y. J., Reddy, M. C., Ioerger, T. R., Rothchild, A. C., Dartois, V., Schuster, B. M., Trauner, A., Wallis, D., Galaviz, S., Huttenhower, C., et al. (2013) · Cell

Tuberculosis Research and EpidemiologyImmune responses and vaccinations

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CsoR is a novel Mycobacterium tuberculosis copper-sensing transcriptional regulator

Liu, T., Ramesh, A., Ma, Z., Ward, S. K., Zhang, L., George, G. N., Talaat, A. M., Sacchettini, J. C., & Giedroc, D. P. (2007) · Nature Chemical Biology

Tuberculosis Research and EpidemiologyBacterial Genetics and Biotechnology

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Altered NADH/NAD + Ratio Mediates Coresistance to Isoniazid and Ethionamide in Mycobacteria

Vilchèze, C., Weisbrod, T. R., Chen, B., Kremer, L., Hazbón, M. H., Wang, F., Alland, D., Sacchettini, J. C., & Jacobs, W. R. (2005) · Antimicrobial Agents and Chemotherapy

Tuberculosis Research and EpidemiologyMycobacterium research and diagnosis

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Crystal Structure and Thermodynamic Analysis of Human Brain Fatty Acid-binding Protein

Balendiran, G. K., Schnütgen, F., Scapin, G., Börchers, T., Xhong, N., Lim, K., Godbout, R., Spener, F., & Sacchettini, J. C. (2000) · Journal of Biological Chemistry

Protein Interaction Studies and Fluorescence AnalysisFatty Acid Research and Health

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Genome-wide Phenotypic Profiling Identifies and Categorizes Genes Required for Mycobacterial Low Iron Fitness

Dragset, M. S., Ioerger, T. R., Zhang, Y. J., Mærk, M., Ginbot, Z., Sacchettini, J. C., Flo, T. H., Rubin, E. J., & Steigedal, M. (2019) · Scientific Reports

Tuberculosis Research and EpidemiologyBacterial Genetics and Biotechnology

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