Kirschning, Carsten J.

Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8

Heil, F., Hemmi, H., Hochrein, H., Ampenberger, F., Kirschning, C., Akira, S., Lipford, G., Wagner, H., & Bauer, S. (2004) · Science

Immune Response and InflammationImmunotherapy and Immune Responses

Cited by 3,947

Peptidoglycan- and Lipoteichoic Acid-induced Cell Activation Is Mediated by Toll-like Receptor 2

Schwandner, R., Dziarski, R., Wesche, H., Rothe, M., & Kirschning, C. J. (1999) · Journal of Biological Chemistry

Immune Response and InflammationNF-κB Signaling Pathways

Cited by 1,704

Endocytosed HSP60s Use Toll-like Receptor 2 (TLR2) and TLR4 to Activate the Toll/Interleukin-1 Receptor Signaling Pathway in Innate Immune Cells

Vabulas, R. M., Ahmad-Nejad, P., da Costa, C., Miethke, T., Kirschning, C. J., Häcker, H., & Wagner, H. (2001) · Journal of Biological Chemistry

Immune Response and InflammationHeat shock proteins research

Cited by 805

Human toll-like receptor 2 confers responsiveness to bacterial lipopolysaccharide

Kirschning, C. J., Wesche, H., Merrill Ayres, T., & Rothe, M. (1998) · The Journal of Experimental Medicine

Immune Response and InflammationNF-κB Signaling Pathways

Cited by 753

Priming of natural killer cells by nonmucosal mononuclear phagocytes requires instructive signals from commensal microbiota

Ganal, S. C., Sanos, S. L., Kallfass, C., Oberle, K., Johner, C., Kirschning, C., Lienenklaus, S., Weiss, S., Staeheli, P., Aichele, P., et al. (2012) · Immunity

Immune Response and Inflammationinterferon and immune responses

Cited by 484

TLR13 Recognizes Bacterial 23 S rRNA Devoid of Erythromycin Resistance–Forming Modification

Oldenburg, M., Krüger, A., Ferstl, R., Kaufmann, A., Nees, G., Sigmund, A., Bathke, B., Lauterbach, H., Suter, M., Dreher, S., et al. (2012) · Science

Immune Response and InflammationRNA and protein synthesis mechanisms

Cited by 405

Mammalian target of rapamycin (mTOR) orchestrates the defense program of innate immune cells

Schmitz, F., Heit, A., Dreher, S., Eisenächer, K., Mages, J., Haas, T., Krug, A., Janssen, K., Kirschning, C. J., & Wagner, H. (2008) · European Journal of Immunology

Immune Response and InflammationPI3K/AKT/mTOR signaling in cancer

Cited by 212

The NLRP3 inflammasome contributes to brain injury in pneumococcal meningitis and is activated through ATP-dependent lysosomal cathepsin B release

Hoegen, T., Tremel, N., Klein, M., Angele, B., Wagner, H., Kirschning, C., Pfister, H.-W., Fontana, A., Hammerschmidt, S., & Koedel, U. (2011) · The Journal of Immunology

Inflammasome and immune disordersBacterial Infections and Vaccines

Cited by 211

Human TLR8 senses UR/URR motifs in bacterial and mitochondrial RNA

Krüger, A., Oldenburg, M., Chebrolu, C., Beisser, D., Kolter, J., Sigmund, A. M., Steinmann, J., Schäfer, S., Hochrein, H., Rahmann, S., et al. (2015) · The EMBO Reports

Immune Response and InflammationInflammasome and immune disorders

Cited by 99

Acute Brain Injury Triggers MyD88-Dependent, TLR2/4-Independent Inflammatory Responses

Koedel, U., Merbt, U. M., Schmidt, C., Angele, B., Popp, B., Wagner, H., Pfister, H.-W., & Kirschning, C. J. (2007) · The American Journal of Pathology

Immune Response and InflammationNeuroinflammation and Neurodegeneration Mechanisms

Cited by 78

Rare TLR2 mutations reduce TLR2 receptor function and can increase atopy risk

Kormann, M. S. D., Ferstl, R., Depner, M., Klopp, N., Spiller, S., Illig, T., Vogelberg, C., Von Mutius, E., Kirschning, C. J., & Kabesch, M. (2009) · Allergy

Immune Response and InflammationDermatology and Skin Diseases

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