Björkhem, Ingemar

Cholesterol homeostasis in human brain: evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulation

Lütjohann, D., Breuer, O., Ahlborg, G., Nennesmo, I., Sidén, A., Diczfalusy, U., & Björkhem, I. (1996) · Proceedings of the National Academy of Sciences

Cholesterol and Lipid MetabolismSteroid Chemistry and Biochemistry

Cited by 682

Cholesterol homeostasis in human brain: turnover of 24S-hydroxycholesterol and evidence for a cerebral origin of most of this oxysterol in the circulation

Björkhem, I., Lütjohann, D., Diczfalusy, U., Ståhle, L., Ahlborg, G., & Wahren, J. (1998) · Journal of Lipid Research

Cholesterol and Lipid MetabolismSteroid Chemistry and Biochemistry

Cited by 538

Cholic acid mediates negative feedback regulation of bile acid synthesis in mice

Li-Hawkins, J., Gåfvels, M., Olin, M., Lund, E. G., Andersson, U., Schuster, G., Björkhem, I., Russell, D. W., & Eggertsen, G. (2002) · Journal of Clinical Investigation

Cholesterol and Lipid MetabolismDrug Transport and Resistance Mechanisms

Cited by 227

Cloning and expression of cDNA of human Δ4‐3‐oxosteroid 5β‐reductase and substrate specificity of the expressed enzyme

KONDO, K., KAI, M., SETOGUCHI, Y., EGGERTSEN, G., SJÖBLOM, P., SETOGUCHI, T., OKUDA, K., & BJÖRKHEM, I. (1994) · European Journal of Biochemistry

Steroid Chemistry and BiochemistryCholesterol and Lipid Metabolism

Cited by 139

Cerebrotendinous xanthomatosis: An inborn error in bile acid synthesis with defined mutations but still a challenge

Björkhem, I., & Hansson, M. (2010) · Biochemical and Biophysical Research Communications

Metabolism and Genetic DisordersCholesterol and Lipid Metabolism

Cited by 92

On the regulatory role of side-chain hydroxylated oxysterols in the brain. Lessons from CYP27A1 transgenic and Cyp27a1(−/−) mice

Ali, Z., Heverin, M., Olin, M., Acimovic, J., Lövgren-Sandblom, A., Shafaati, M., Båvner, A., Meiner, V., Leitersdorf, E., & Björkhem, I. (2013) · Journal of Lipid Research

Cholesterol and Lipid MetabolismSteroid Chemistry and Biochemistry

Cited by 54

On the fluxes of side-chain oxidized oxysterols across blood-brain and blood-CSF barriers and origin of these steroids in CSF (Review)

Björkhem, I., Leoni, V., & Svenningsson, P. (2019) · The Journal of Steroid Biochemistry and Molecular Biology

Cholesterol and Lipid MetabolismBarrier Structure and Function Studies

Cited by 47