Lees, Kennedy R.

Thrombolysis with Alteplase 3 to 4.5 Hours after Acute Ischemic Stroke

Hacke, W., Kaste, M., Bluhmki, E., Brozman, M., Dávalos, A., Guidetti, D., Larrue, V., Lees, K. R., Medeghri, Z., Machnig, T., et al. (2008) · New England Journal of Medicine

Acute Ischemic Stroke ManagementIntracerebral and Subarachnoid Hemorrhage Research

Cited by 6,684

Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials

Emberson, J., Lees, K. R., Lyden, P., Blackwell, L., Albers, G., Bluhmki, E., Brott, T., Cohen, G., Davis, S., Donnan, G., et al. (2014) · The Lancet

Acute Ischemic Stroke ManagementIntracerebral and Subarachnoid Hemorrhage Research

Cited by 2,737

NXY-059 for Acute Ischemic Stroke

Lees, K. R., Zivin, J. A., Ashwood, T., Davalos, A., Davis, S. M., Diener, H.-C., Grotta, J., Lyden, P., Shuaib, A., Hårdemark, H.-G., et al. (2006) · New England Journal of Medicine

Acute Ischemic Stroke ManagementNeuroprotection in Cerebral Ischemia

Cited by 660

Detection of Atrial Fibrillation After Ischemic Stroke or Transient Ischemic Attack: A Systematic Review and Meta-Analysis

Kishore, A., Vail, A., Majid, A., Dawson, J., Lees, K. R., Tyrrell, P. J., & Smith, C. J. (2014) · Stroke

Atrial Fibrillation Management and OutcomesAcute Ischemic Stroke Management

Cited by 374

Statistical Analysis of the Primary Outcome in Acute Stroke Trials

Bath, P. M. W., Lees, K. R., Schellinger, P. D., Altman, H., Bland, M., Hogg, C., Howard, G., & Saver, J. L. (2012) · Stroke

Acute Ischemic Stroke ManagementVenous Thromboembolism Diagnosis and Management

Cited by 266

Contemporary Outcome Measures in Acute Stroke Research: Choice of Primary Outcome Measure

Lees, K. R., Bath, P. M. W., Schellinger, P. D., Kerr, D. M., Fulton, R., Hacke, W., Matchar, D., Sehra, R., & Toni, D. (2012) · Stroke

Acute Ischemic Stroke ManagementStroke Rehabilitation and Recovery

Cited by 242

Xanthine Oxidase Inhibition For The Treatment Of Cardiovascular Disease: A Systematic Review and Meta‐Analysis

Higgins, P., Dawson, J., Lees, K. R., McArthur, K., Quinn, T. J., & Walters, M. R. (2012) · Cardiovascular Therapeutics

Gout, Hyperuricemia, Uric AcidCardiovascular Health and Disease Prevention

Cited by 164

Robotic Measurement of Arm Movements After Stroke Establishes Biomarkers of Motor Recovery

Krebs, H. I., Krams, M., Agrafiotis, D. K., DiBernardo, A., Chavez, J. C., Littman, G. S., Yang, E., Byttebier, G., Dipietro, L., Rykman, A., et al. (2014) · Stroke

Stroke Rehabilitation and RecoveryMotor Control and Adaptation

Cited by 154

Comparison of stratification and adaptive methods for treatment allocation in an acute stroke clinical trial

Weir, C. J., & Lees, K. R. (2003) · Statistics in Medicine

Statistical Methods in Clinical TrialsOptimal Experimental Design Methods

Cited by 102

METACOHORTS for the study of vascular disease and its contribution to cognitive decline and neurodegeneration: An initiative of the Joint Programme for Neurodegenerative Disease Research

METACOHORTS Consortium, Dichgans, M., Wardlaw, J., Smith, E., Zietemann, V., Seshadri, S., Sachdev, P., Biessels, G. J., Fazekas, F., Benavente, O., et al. (2016) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchNeurological Disease Mechanisms and Treatments

Cited by 101

Seven-Day NIHSS Is a Sensitive Outcome Measure for Exploratory Clinical Trials in Acute Stroke: Evidence From the Virtual International Stroke Trials Archive

Kerr, D. M., Fulton, R. L., Lees, K. R., & Collaborators, F. T. V. (2012) · Stroke

Acute Ischemic Stroke ManagementStatistical Methods in Clinical Trials

Cited by 93

Improving Trial Power Through Use of Prognosis-Adjusted End Points

Young, F. B., Lees, K. R., & Weir, C. J. (2005) · Stroke

Statistical Methods in Clinical TrialsAcute Ischemic Stroke Management

Cited by 44

Targeting Neuroprotection Clinical Trials to Ischemic Stroke Patients With Potential to Benefit From Therapy

Weir, C. J., Kaste, M., & Lees, K. R. (2004) · Stroke

Acute Ischemic Stroke ManagementStatistical Methods in Clinical Trials

Cited by 31

Efficacy and safety of digoxin in patients with heart failure and reduced ejection fraction according to diabetes status: an analysis of the Digitalis Investigation Group (DIG) trial

Abdul-Rahim, A. H., MacIsaac, R. L., Jhund, P. S., Petrie, M. C., Lees, K. R., & McMurray, J. J. V. (2016) · International Journal of Cardiology

Heart Failure Treatment and ManagementHeart rate and cardiovascular health

Cited by 29

Using the Barthel Index and modified Rankin Scale as Outcome Measures for Stroke Rehabilitation Trials; A Comparison of Minimum Sample Size Requirements

McGill, K., Sackley, C., Godwin, J., Gavaghan, D., Ali, M., Ballester, B. R., Brady, M. C., Brady, M. C., Ali, M., Ashburn, A., et al. (2022) · Journal of Stroke and Cerebrovascular Diseases

Statistical Methods in Clinical TrialsStroke Rehabilitation and Recovery

Cited by 14