Chu, Gerald C.
Brigham and Women's Hospital · Harvard University
9 papers on CoChat
Most cited papers
- Verified
Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism
Ying, H., Kimmelman, A. C., Lyssiotis, C. A., Hua, S., Chu, G. C., Fletcher-Sananikone, E., Locasale, J. W., Son, J., Zhang, H., Coloff, J. L., et al. (2012) · Cell
Pancreatic and Hepatic Oncology ResearchCancer, Hypoxia, and Metabolism
Cited by 2,043
- Verified
p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation
Zheng, H., Ying, H., Yan, H., Kimmelman, A. C., Hiller, D. J., Chen, A.-J., Perry, S. R., Tonon, G., Chu, G. C., Ding, Z., et al. (2008) · Nature
Glioma Diagnosis and TreatmentCancer-related Molecular Pathways
Cited by 767
- Verified
Yap1 Activation Enables Bypass of Oncogenic Kras Addiction in Pancreatic Cancer
Kapoor, A., Yao, W., Ying, H., Hua, S., Liewen, A., Wang, Q., Zhong, Y., Wu, C.-J., Sadanandam, A., Hu, B., et al. (2014) · Cell
Hippo pathway signaling and YAP/TAZPancreatic and Hepatic Oncology Research
Cited by 716
- Verified
Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer
Bardeesy, N., Cheng, K.-H., Berger, J. H., Chu, G. C., Pahler, J., Olson, P., Hezel, A. F., Horner, J., Lauwers, G. Y., Hanahan, D., et al. (2006) · Genes & Development
Pancreatic and Hepatic Oncology ResearchTGF-β signaling in diseases
Cited by 674
- Verified
Autophagy is critical for pancreatic tumor growth and progression in tumors with p53 alterations
Yang, A., Rajeshkumar, N. V., Wang, X., Yabuuchi, S., Alexander, B. M., Chu, G. C., Von Hoff, D. D., Maitra, A., & Kimmelman, A. C. (2014) · Cancer Discovery
Autophagy in Disease and TherapyPancreatic and Hepatic Oncology Research
Cited by 486
- Verified
Oncogenic NRAS signaling differentially regulates survival and proliferation in melanoma
Kwong, L. N., Costello, J. C., Liu, H., Jiang, S., Helms, T. L., Langsdorf, A. E., Jakubosky, D., Genovese, G., Muller, F. L., Jeong, J. H., et al. (2012) · Nature Medicine
Melanoma and MAPK PathwaysProtein Kinase Regulation and GTPase Signaling
Cited by 358
- Verified
Compensatory metabolic networks in pancreatic cancers upon perturbation of glutamine metabolism
Biancur, D. E., Paulo, J. A., Małachowska, B., Quiles Del Rey, M., Sousa, C. M., Wang, X., Sohn, A. S. W., Chu, G. C., Gygi, S. P., Harper, J. W., et al. (2017) · Nature Communications
Cancer, Hypoxia, and MetabolismPancreatic and Hepatic Oncology Research
Cited by 315
- Verified
Telomerase Reactivation following Telomere Dysfunction Yields Murine Prostate Tumors with Bone Metastases
Ding, Z., Wu, C.-J., Jaskelioff, M., Ivanova, E., Kost-Alimova, M., Protopopov, A., Chu, G. C., Wang, G., Lu, X., Labrot, E. S., et al. (2012) · Cell
Telomeres, Telomerase, and SenescenceProstate Cancer Treatment and Research
Cited by 220
- Verified
Oncogenic Kras drives invasion and maintains metastases in colorectal cancer
Boutin, A. T., Liao, W.-T., Wang, M., Hwang, S. S., Karpinets, T. V., Cheung, H., Chu, G. C., Jiang, S., Hu, J., Chang, K., et al. (2017) · Genes & Development
Colorectal Cancer Treatments and StudiesProtein Kinase Regulation and GTPase Signaling
Cited by 195
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