Crowley, Jan R.

Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41

Samuel, B. S., Shaito, A., Motoike, T., Rey, F. E., Backhed, F., Manchester, J. K., Hammer, R. E., Williams, S. C., Crowley, J., Yanagisawa, M., et al. (2008) · Proceedings of the National Academy of Sciences

Gut microbiota and healthRegulation of Appetite and Obesity

Cited by 1,564

Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis

Sergin, I., Evans, T. D., Zhang, X., Bhattacharya, S., Stokes, C. J., Song, E., Ali, S., Dehestani, B., Holloway, K. B., Micevych, P. S., et al. (2017) · Nature Communications

Autophagy in Disease and TherapyAtherosclerosis and Cardiovascular Diseases

Cited by 351

The siderophore yersiniabactin binds copper to protect pathogens during infection

Chaturvedi, K. S., Hung, C. S., Crowley, J. R., Stapleton, A. E., & Henderson, J. P. (2012) · Nature Chemical Biology

Escherichia coli research studiesBacterial Genetics and Biotechnology

Cited by 301

Trehalose inhibits solute carrier 2A (SLC2A) proteins to induce autophagy and prevent hepatic steatosis

DeBosch, B. J., Heitmeier, M. R., Mayer, A. L., Higgins, C. B., Crowley, J. R., Kraft, T. E., Chi, M., Newberry, E. P., Chen, Z., Finck, B. N., et al. (2016) · Science Signaling

Autophagy in Disease and TherapyMetabolism, Diabetes, and Cancer

Cited by 280

Regulation of myocardial ketone body metabolism by the gut microbiota during nutrient deprivation

Crawford, P. A., Crowley, J. R., Sambandam, N., Muegge, B. D., Costello, E. K., Hamady, M., Knight, R., & Gordon, J. I. (2009) · Proceedings of the National Academy of Sciences

Gut microbiota and healthDiet and metabolism studies

Cited by 278

High-protein diets increase cardiovascular risk by activating macrophage mTOR to suppress mitophagy

Zhang, X., Sergin, I., Evans, T. D., Jeong, S.-J., Rodriguez-Velez, A., Kapoor, D., Chen, S., Song, E., Holloway, K. B., Crowley, J. R., et al. (2020) · Nature Metabolism

Atherosclerosis and Cardiovascular DiseasesAutophagy in Disease and Therapy

Cited by 191

A high-throughput fluorimetric assay for 2-hydroxyglutarate identifies Zaprinast as a glutaminase inhibitor

Elhammali, A., Ippolito, J. E., Collins, L., Crowley, J., Marasa, J., & Piwnica-Worms, D. (2014) · Cancer Discovery

Cancer, Hypoxia, and MetabolismGlioma Diagnosis and Treatment

Cited by 77

Metal selectivity by the virulence-associated yersiniabactin metallophore system

Koh, E.-I., Hung, C. S., Parker, K. S., Crowley, J. R., Giblin, D. E., & Henderson, J. P. (2015) · Metallomics

Bacterial Genetics and BiotechnologyEscherichia coli research studies

Cited by 75

Direct tests of enzymatic heme degradation by the malaria parasite Plasmodium falciparum

Sigala, P. A., Crowley, J. R., Hsieh, S., Henderson, J. P., & Goldberg, D. E. (2012) · Journal of Biological Chemistry

Malaria Research and ControlHeme Oxygenase-1 and Carbon Monoxide

Cited by 68

Human Urinary Composition Controls Antibacterial Activity of Siderocalin*

Shields-Cutler, R. R., Crowley, J. R., Hung, C. S., Stapleton, A. E., Aldrich, C. C., Marschall, J., & Henderson, J. P. (2015) · Journal of Biological Chemistry

Urinary Tract Infections ManagementEscherichia coli research studies

Cited by 56

Leukotoxin diols from ground corncob bedding disrupt estrous cyclicity in rats and stimulate MCF-7 breast cancer cell proliferation

Markaverich, B. M., Crowley, J. R., Alejandro, M. A., Shoulars, K., Casajuna, N., Mani, S., Reyna, A., & Sharp, J. (2005) · Environmental Health Perspectives

Effects and risks of endocrine disrupting chemicalsEstrogen and related hormone effects

Cited by 53