Jansen, Peter L. M.

Bile acid receptors as targets for drug development

Schaap, F. G., Trauner, M., & Jansen, P. L. M. (2014) · Nature Reviews Gastroenterology & Hepatology

Drug Transport and Resistance MechanismsCholesterol and Lipid Metabolism

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Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport.

Müller, M., Meijer, C., Zaman, G. J., Borst, P., Scheper, R. J., Mulder, N. H., de Vries, E. G., & Jansen, P. L. (1994) · Proceedings of the National Academy of Sciences

Drug Transport and Resistance MechanismsGlutathione Transferases and Polymorphisms

Cited by 617

New paradigms in the treatment of hepatic cholestasis: from UDCA to FXR, PXR and beyond

Beuers, U., Trauner, M., Jansen, P., & Poupon, R. (2015) · Journal of Hepatology

Drug Transport and Resistance MechanismsLiver Diseases and Immunity

Cited by 537

The Biliary HCO3 − Umbrella: A Unifying Hypothesis on Pathogenetic and Therapeutic Aspects of Fibrosing Cholangiopathies

Beuers, U., Hohenester, S., de Buy Wenniger, L. J. M., Kremer, A. E., Jansen, P. L. M., & Elferink, R. P. J. O. (2010) · Hepatology

Liver Diseases and ImmunityDrug Transport and Resistance Mechanisms

Cited by 351

The ascending pathophysiology of cholestatic liver disease

Jansen, P. L. M., Ghallab, A., Vartak, N., Reif, R., Schaap, F. G., Hampe, J., & Hengstler, J. G. (2017) · Hepatology

Liver Diseases and ImmunityDrug Transport and Resistance Mechanisms

Cited by 301

Tauroursodeoxycholic acid protects rat hepatocytes from bile acid–induced apoptosis via activation of survival pathways

Schoemaker, M. H., de la Rosa, L. C., Buist-Homan, M., Vrenken, T. E., Havinga, R., Poelstra, K., Haisma, H. J., Jansen, P. L. M., & Moshage, H. (2004) · Hepatology

Drug Transport and Resistance MechanismsAldose Reductase and Taurine

Cited by 229

Bile Microinfarcts in Cholestasis Are Initiated by Rupture of the Apical Hepatocyte Membrane and Cause Shunting of Bile to Sinusoidal Blood

Ghallab, A., Hofmann, U., Sezgin, S., Vartak, N., Hassan, R., Zaza, A., Godoy, P., Schneider, K. M., Guenther, G., Ahmed, Y. A., et al. (2019) · Hepatology

Liver physiology and pathologyLiver Diseases and Immunity

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