Chen, Hua Tang

53BP1 Inhibits Homologous Recombination in Brca1-Deficient Cells by Blocking Resection of DNA Breaks

Bunting, S. F., Callén, E., Wong, N., Chen, H.-T., Polato, F., Gunn, A., Bothmer, A., Feldhahn, N., Fernandez-Capetillo, O., Cao, L., et al. (2010) · Cell

DNA Repair MechanismsPARP inhibition in cancer therapy

Cited by 1,671

Genomic Instability in Mice Lacking Histone H2AX

Celeste, A., Petersen, S., Romanienko, P. J., Fernandez-Capetillo, O., Chen, H. T., Sedelnikova, O. A., Reina-San-Martin, B., Coppola, V., Meffre, E., Difilippantonio, M. J., et al. (2002) · Science

DNA Repair MechanismsEffects of Radiation Exposure

Cited by 1,385

Phosphorylation of histone H2AX and activation of Mre11, Rad50, and Nbs1 in response to replication-dependent DNA double-strand breaks induced by mammalian DNA topoisomerase I cleavage complexes

Furuta, T., Takemura, H., Liao, Z.-Y., Aune, G. J., Redon, C., Sedelnikova, O. A., Pilch, D. R., Rogakou, E. P., Celeste, A., Chen, H. T., et al. (2003) · Journal of Biological Chemistry

DNA Repair MechanismsCancer therapeutics and mechanisms

Cited by 449

Regulation of DNA End Joining, Resection, and Immunoglobulin Class Switch Recombination by 53BP1

Bothmer, A., Robbiani, D. F., Di Virgilio, M., Bunting, S. F., Klein, I. A., Feldhahn, N., Barlow, J., Chen, H.-T., Bosque, D., Callen, E., et al. (2011) · Molecular Cell

DNA Repair MechanismsEffects of Radiation Exposure

Cited by 244

Genetic interactions between ATM and the nonhomologous end-joining factors in genomic stability and development

Sekiguchi, J., Ferguson, D. O., Chen, H. T., Yang, E. M., Earle, J., Frank, K., Whitlow, S., Gu, Y., Xu, Y., Nussenzweig, A., et al. (2001) · Proceedings of the National Academy of Sciences

DNA Repair MechanismsEffects of Radiation Exposure

Cited by 156