Neumann, Lars

Histone Deacetylase (HDAC) Inhibitor Kinetic Rate Constants Correlate with Cellular Histone Acetylation but Not Transcription and Cell Viability

Lauffer, B. E. L., Mintzer, R., Fong, R., Mukund, S., Tam, C., Zilberleyb, I., Flicke, B., Ritscher, A., Fedorowicz, G., Vallero, R., et al. (2013) · Journal of Biological Chemistry

Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics

Cited by 429

HTS reporter displacement assay for fragment screening and fragment evolution toward leads with optimized binding kinetics, binding selectivity, and thermodynamic signature

Neumann, L., von König, K., & Ullmann, D. (2011) · Methods in Enzymology

thermodynamics and calorimetric analysesComputational Drug Discovery Methods

Cited by 51

Fragment-based lead generation: identification of seed fragments by a highly efficient fragment screening technology

Neumann, L., Ritscher, A., Müller, G., & Hafenbradl, D. (2009) · Journal of Computer-Aided Molecular Design

Computational Drug Discovery MethodsChemical Synthesis and Analysis

Cited by 20