Zhang, Xian-Man

Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase

Madiraju, A. K., Erion, D. M., Rahimi, Y., Zhang, X.-M., Braddock, D. T., Albright, R. A., Prigaro, B. J., Wood, J. L., Bhanot, S., MacDonald, M. J., et al. (2014) · Nature

Metabolism, Diabetes, and CancerDiabetes Treatment and Management

Cited by 1,284

Hepatic acetyl CoA links adipose tissue inflammation to hepatic insulin resistance and type 2 diabetes

Perry, R. J., Camporez, J.-P. G., Kursawe, R., Titchenell, P. M., Zhang, D., Perry, C. J., Jurczak, M. J., Abudukadier, A., Han, M. S., Zhang, X.-M., et al. (2015) · Cell

Adipokines, Inflammation, and Metabolic DiseasesLipid metabolism and biosynthesis

Cited by 719

Inhibition of protein kinase Cε prevents hepatic insulin resistance in nonalcoholic fatty liver disease

Samuel, V. T., Liu, Z.-X., Wang, A., Beddow, S. A., Geisler, J. G., Kahn, M., Zhang, X.-M., Monia, B. P., Bhanot, S., & Shulman, G. I. (2007) · Journal of Clinical Investigation

Liver Disease Diagnosis and TreatmentMetabolism, Diabetes, and Cancer

Cited by 497

Apolipoprotein C3 gene variants in nonalcoholic fatty liver disease

Petersen, K. F., Dufour, S., Hariri, A., Nelson-Williams, C., Foo, J. N., Zhang, X.-M., Dziura, J., Lifton, R. P., & Shulman, G. I. (2010) · New England Journal of Medicine

Liver Disease Diagnosis and TreatmentLipid metabolism and disorders

Cited by 428

Suppression of Diacylglycerol Acyltransferase-2 (DGAT2), but Not DGAT1, with Antisense Oligonucleotides Reverses Diet-induced Hepatic Steatosis and Insulin Resistance

Choi, C. S., Savage, D. B., Kulkarni, A., Yu, X. X., Liu, Z.-X., Morino, K., Kim, S., Distefano, A., Samuel, V. T., Neschen, S., et al. (2007) · Journal of Biological Chemistry

Liver Disease Diagnosis and TreatmentLipid metabolism and biosynthesis

Cited by 383

Controlled-release mitochondrial protonophore reverses diabetes and steatohepatitis in rats

Perry, R. J., Zhang, D., Zhang, X.-M., Boyer, J. L., & Shulman, G. I. (2015) · Science

Liver Disease Diagnosis and TreatmentMetabolism, Diabetes, and Cancer

Cited by 283

Prevention of hepatic steatosis and hepatic insulin resistance in mitochondrial acyl-CoA:glycerol-sn-3-phosphate acyltransferase 1 knockout mice

Neschen, S., Morino, K., Hammond, L. E., Zhang, D., Liu, Z.-X., Romanelli, A. J., Cline, G. W., Pongratz, R. L., Zhang, X.-M., Choi, C. S., et al. (2005) · Cell Metabolism

Liver Disease Diagnosis and TreatmentLipid metabolism and biosynthesis

Cited by 261

Glucagon stimulates gluconeogenesis by INSP3R1-mediated hepatic lipolysis

Perry, R. J., Zhang, D., Guerra, M. T., Brill, A. L., Goedeke, L., Nasiri, A. R., Rabin-Court, A., Wang, Y., Peng, L., Dufour, S., et al. (2020) · Nature

Metabolism, Diabetes, and CancerPancreatic function and diabetes

Cited by 186

Propionate increases hepatic pyruvate cycling and anaplerosis and alters mitochondrial metabolism

Perry, R. J., Borders, C. B., Cline, G. W., Zhang, X.-M., Alves, T. C., Petersen, K. F., Rothman, D. L., Kibbey, R. G., & Shulman, G. I. (2016) · Journal of Biological Chemistry

Metabolism, Diabetes, and CancerMetabolomics and Mass Spectrometry Studies

Cited by 78