Chen, Chih-Chiun

Functions and mechanisms of action of CCN matricellular proteins

Chen, C.-C., & Lau, L. F. (2009) · The International Journal of Biochemistry & Cell Biology

Connective Tissue Growth Factor ResearchBone and Dental Protein Studies

Cited by 549

CYR61 (CCN1) Is Essential for Placental Development and Vascular Integrity

Mo, F.-E., Muntean, A. G., Chen, C.-C., Stolz, D. B., Watkins, S. C., & Lau, L. F. (2002) · Molecular and Cellular Biology

Connective Tissue Growth Factor ResearchPregnancy and preeclampsia studies

Cited by 416

The Angiogenic Factors Cyr61 and Connective Tissue Growth Factor Induce Adhesive Signaling in Primary Human Skin Fibroblasts

Chen, C.-C., Chen, N., & Lau, L. F. (2001) · Journal of Biological Chemistry

Connective Tissue Growth Factor ResearchCell Adhesion Molecules Research

Cited by 305

The Angiogenic Factor Cyr61 Activates a Genetic Program for Wound Healing in Human Skin Fibroblasts

Chen, C.-C., Mo, F.-E., & Lau, L. F. (2001) · Journal of Biological Chemistry

Connective Tissue Growth Factor ResearchWound Healing and Treatments

Cited by 300

Matricellular Protein CCN1 Promotes Regression of Liver Fibrosis through Induction of Cellular Senescence in Hepatic Myofibroblasts

Kim, K.-H., Chen, C.-C., Monzon, R. I., & Lau, L. F. (2013) · Molecular and Cellular Biology

Liver physiology and pathologyConnective Tissue Growth Factor Research

Cited by 261

Activation-dependent Adhesion of Human Platelets to Cyr61 and Fisp12/Mouse Connective Tissue Growth Factor Is Mediated through Integrin αIIbβ3

Jedsadayanmata, A., Chen, C.-C., Kireeva, M. L., Lau, L. F., & Lam, S. C.-T. (1999) · Journal of Biological Chemistry

Platelet Disorders and TreatmentsCell Adhesion Molecules Research

Cited by 204

Adhesion of Human Skin Fibroblasts to Cyr61 Is Mediated through Integrin α6β1 and Cell Surface Heparan Sulfate Proteoglycans

Chen, N., Chen, C.-C., & Lau, L. F. (2000) · Journal of Biological Chemistry

Connective Tissue Growth Factor ResearchCell Adhesion Molecules Research

Cited by 195

Matricellular Protein CCN1 Activates a Proinflammatory Genetic Program in Murine Macrophages

Bai, T., Chen, C.-C., & Lau, L. F. (2010) · The Journal of Immunology

Connective Tissue Growth Factor ResearchSignaling Pathways in Disease

Cited by 173

Cytotoxicity of TNFα is regulated by integrin‐mediated matrix signaling

Chen, C., Young, J. L., Monzon, R. I., Chen, N., Todorović, V., & Lau, L. F. (2007) · The EMBO Journal

Connective Tissue Growth Factor ResearchCell death mechanisms and regulation

Cited by 143

The matrix protein CCN1 (CYR61) induces apoptosis in fibroblasts

Todorovicç, V., Chen, C.-C., Hay, N., & Lau, L. F. (2005) · The Journal of Cell Biology

Connective Tissue Growth Factor ResearchCell death mechanisms and regulation

Cited by 132

Identification of a novel integrin α6β1 binding site in the angiogenic Inducer CCN1 (CYR61)

Leu, S.-J., Liu, Y., Chen, N., Chen, C.-C., Lam, S. C.-T., & Lau, L. F. (2003) · Journal of Biological Chemistry

Connective Tissue Growth Factor ResearchCell Adhesion Molecules Research

Cited by 131

CCN1 induces hepatic ductular reaction through integrin αvβ5–mediated activation of NF-κB

Kim, K.-H., Chen, C.-C., Alpini, G., & Lau, L. F. (2015) · Journal of Clinical Investigation

Liver physiology and pathologyConnective Tissue Growth Factor Research

Cited by 109

Targeted Mutagenesis of the Angiogenic Protein CCN1 (CYR61)

Leu, S.-J., Chen, N., Chen, C.-C., Todorović, V., Bai, T., Juric, V., Liu, Y., Yan, G., Lam, S. C.-T., & Lau, L. F. (2004) · Journal of Biological Chemistry

Connective Tissue Growth Factor ResearchBone and Dental Protein Studies

Cited by 72

Fas-Mediated Apoptosis Is Regulated by the Extracellular Matrix Protein CCN1 (CYR61) In Vitro and In Vivo

Juric, V., Chen, C.-C., & Lau, L. F. (2009) · Molecular and Cellular Biology

Connective Tissue Growth Factor ResearchCell death mechanisms and regulation

Cited by 70

Matrix Protein CCN1 Is Critical for Prostate Carcinoma Cell Proliferation and TRAIL-Induced Apoptosis

Franzen, C. A., Chen, C.-C., Todorović, V., Juric, V., Monzon, R. I., & Lau, L. F. (2009) · Molecular Cancer Research

Connective Tissue Growth Factor ResearchBone and Dental Protein Studies

Cited by 66

Deadly liaisons: fatal attraction between CCN matricellular proteins and the tumor necrosis factor family of cytokines

Chen, C., & Lau, L. F. (2010) · Journal of Cell Communication and Signaling

Connective Tissue Growth Factor ResearchCell death mechanisms and regulation

Cited by 47

The Extracellular Matrix Protein CCN1 Dictates TNFα and FasL Cytotoxicity In Vivo

Chen, C.-C., Juric, V., & Lau, L. F. (2011) · Advances in Experimental Medicine and Biology

Connective Tissue Growth Factor ResearchCell death mechanisms and regulation

Cited by 8